Future laser-accelerated proton beams at ELI-Beamlines as potential source of positron emitters for PET

E. Amato, A. Italiano*, D. Margarone, B. Pagano, S. Baldari, G. Korn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The development of novel compact PET radionuclide production systems is of great interest to promote the diffusion of PET diagnostics, especially in view of the continuous development of novel, fast and efficient, radiopharmaceutical methods of labeling. We studied the feasibility to produce clinically-relevant amounts of PET isotopes by means of laser-accelerated proton sources expected at the ELI-Beamlines facility where a PW, 30 fs, 10 Hz laser system will be available. The production yields of several positron emitters were calculated through the TALYS software, by taking into account three possible scenarios of broad proton spectra expected, with maximum energies ranging from about 8 MeV to 100 MeV. With the hypothesized proton fluencies, clinically-relevant amounts of radionuclides can be obtained, suitable to prepare single doses of radiopharmaceuticals exploiting modern fast and efficient labeling systems.

Original languageEnglish
Article numberC04007
JournalJournal of Instrumentation
Volume11
Issue number4
DOIs
Publication statusPublished - 11 Apr 2016
Externally publishedYes

Keywords

  • Accelerator applications
  • Radiotherapy concepts

ASJC Scopus subject areas

  • Mathematical Physics
  • Instrumentation

Fingerprint

Dive into the research topics of 'Future laser-accelerated proton beams at ELI-Beamlines as potential source of positron emitters for PET'. Together they form a unique fingerprint.

Cite this