Abstract
Pituitary tumours are relatively common in the general population. Most often they occur sporadically, with somatic mutations accounting for a significant minority of somatotroph and corticotroph adenomas. Pituitary tumours can also develop secondary to germline mutations as part of a complex syndrome or as familial isolated pituitary adenomas. Tumours occurring in a familial setting may present at a younger age and can behave more aggressively with resistance to treatment. This chapter will focus on the genetics and molecular pathogenesis of pituitary tumours.
| Original language | English |
|---|---|
| Title of host publication | Genetics of Endocrine Diseases and Syndromes |
| Editors | Peter Igaz, Attila Patocs |
| Publisher | Springer |
| Pages | 171-211 |
| Number of pages | 41 |
| Volume | 111 |
| ISBN (Electronic) | 978-3-030-25905-1 |
| DOIs | |
| Publication status | Published - 07 Oct 2019 |
| Externally published | Yes |
Publication series
| Name | Experientia Supplementum |
|---|---|
| Publisher | Springer International Publishing AG |
| ISSN (Print) | 1664-431X |
Keywords
- FIPA
- AIP
- GPR101
- Gigantism
- Acromegaly
- Prolactinoma
- Succinate Dehydrogenase
- Neuroendocrinology
- McCune-Albright
- Carney Complex
- GNAS
- USP8
- Cushing's
- Cushing's disease
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Dive into the research topics of 'Genetics of Pituitary Tumours'. Together they form a unique fingerprint.Student theses
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Clinical, genetic and molecular correlations in pituitary neuroendocrine tumours
Loughrey, P. B. (Author), James, J. (Supervisor), Craig, S. (Supervisor), Korbonits, M. (Supervisor) & Hunter, S. (Supervisor), Dec 2023Student thesis: Doctoral Thesis › Doctor of Philosophy