Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

P. Abad; J. Gouzy; J.M. Aury; P. Castagnone-Sereno; E.G.J. Danchin; E. Deleury; L. Perfus-Barbeoch; V. Anthouard; F. Artiguenave; V.C. Blok; M.C. Caillaud; P.M. Coutinho; C. Dasilva; F. De Luca; F. Deau; M. Esquibet; T. Flutre; J.V. Goldstone; N. Hamamouch; T. Hewezi; O. Jaillon; C. Jubin; P. Leonetti; M. Magliano; T.R. Maier; G.V. Markov; Paul McVeigh; G. Pesole; J. Poulain; M. Robinson-Rechavi; E. Sallet; B. Segurens; D. Steinbach; T. Tytgat; E. Ugarte; C. Van Ghelder; P. Veronico; T.J. Baum; M. Blaxter; T. Bleve-Zacheo; E.L. Davis; J.J. Ewbank; B. Favery; E. Grenier; B. Henrissat; J.T. Jones; V. Laudet; Aaron Maule; H. Quesneville; M.N. Rosso; T. Schiex; G. Smant; J. Weissenbach; P. Wincker

doi:10.1038/nbt.1482

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

P. Abad, J. Gouzy, J.M. Aury, P. Castagnone-Sereno, E.G.J. Danchin, E. Deleury, L. Perfus-Barbeoch, V. Anthouard, F. Artiguenave, V.C. Blok, M.C. Caillaud, P.M. Coutinho, C. Dasilva, F. De Luca, F. Deau, M. Esquibet, T. Flutre, J.V. Goldstone, N. Hamamouch, T. HeweziO. Jaillon, C. Jubin, P. Leonetti, M. Magliano, T.R. Maier, G.V. Markov, Paul McVeigh, G. Pesole, J. Poulain, M. Robinson-Rechavi, E. Sallet, B. Segurens, D. Steinbach, T. Tytgat, E. Ugarte, C. Van Ghelder, P. Veronico, T.J. Baum, M. Blaxter, T. Bleve-Zacheo, E.L. Davis, J.J. Ewbank, B. Favery, E. Grenier, B. Henrissat, J.T. Jones, V. Laudet, Aaron Maule, H. Quesneville, M.N. Rosso, T. Schiex, G. Smant, J. Weissenbach, P. Wincker

School of Biological Sciences

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Abstract

Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

Original language	English
Pages (from-to)	909-915
Number of pages	7
Journal	Nature Biotechnology
Volume	26
Issue number	8
Early online date	27 Jul 2008
DOIs	https://doi.org/10.1038/nbt.1482
Publication status	Published - 2008

ASJC Scopus subject areas

Microbiology

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Abad, P., Gouzy, J., Aury, J. M., Castagnone-Sereno, P., Danchin, E. G. J., Deleury, E., Perfus-Barbeoch, L., Anthouard, V., Artiguenave, F., Blok, V. C., Caillaud, M. C., Coutinho, P. M., Dasilva, C., De Luca, F., Deau, F., Esquibet, M., Flutre, T., Goldstone, J. V., Hamamouch, N., ... Wincker, P. (2008). Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Nature Biotechnology, 26(8), 909-915. https://doi.org/10.1038/nbt.1482

@article{1e8e26b92cdb471591b3a7933d7aa438,

title = "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita",

abstract = "Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.",

author = "P. Abad and J. Gouzy and J.M. Aury and P. Castagnone-Sereno and E.G.J. Danchin and E. Deleury and L. Perfus-Barbeoch and V. Anthouard and F. Artiguenave and V.C. Blok and M.C. Caillaud and P.M. Coutinho and C. Dasilva and {De Luca}, F. and F. Deau and M. Esquibet and T. Flutre and J.V. Goldstone and N. Hamamouch and T. Hewezi and O. Jaillon and C. Jubin and P. Leonetti and M. Magliano and T.R. Maier and G.V. Markov and Paul McVeigh and G. Pesole and J. Poulain and M. Robinson-Rechavi and E. Sallet and B. Segurens and D. Steinbach and T. Tytgat and E. Ugarte and {Van Ghelder}, C. and P. Veronico and T.J. Baum and M. Blaxter and T. Bleve-Zacheo and E.L. Davis and J.J. Ewbank and B. Favery and E. Grenier and B. Henrissat and J.T. Jones and V. Laudet and Aaron Maule and H. Quesneville and M.N. Rosso and T. Schiex and G. Smant and J. Weissenbach and P. Wincker",

year = "2008",

doi = "10.1038/nbt.1482",

language = "English",

volume = "26",

pages = "909--915",

journal = "Nature Biotechnology",

issn = "1087-0156",

publisher = "Nature Research",

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Abad, P, Gouzy, J, Aury, JM, Castagnone-Sereno, P, Danchin, EGJ, Deleury, E, Perfus-Barbeoch, L, Anthouard, V, Artiguenave, F, Blok, VC, Caillaud, MC, Coutinho, PM, Dasilva, C, De Luca, F, Deau, F, Esquibet, M, Flutre, T, Goldstone, JV, Hamamouch, N, Hewezi, T, Jaillon, O, Jubin, C, Leonetti, P, Magliano, M, Maier, TR, Markov, GV, McVeigh, P, Pesole, G, Poulain, J, Robinson-Rechavi, M, Sallet, E, Segurens, B, Steinbach, D, Tytgat, T, Ugarte, E, Van Ghelder, C, Veronico, P, Baum, TJ, Blaxter, M, Bleve-Zacheo, T, Davis, EL, Ewbank, JJ, Favery, B, Grenier, E, Henrissat, B, Jones, JT, Laudet, V, Maule, A, Quesneville, H, Rosso, MN, Schiex, T, Smant, G, Weissenbach, J & Wincker, P 2008, 'Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita', Nature Biotechnology, vol. 26, no. 8, pp. 909-915. https://doi.org/10.1038/nbt.1482

TY - JOUR

T1 - Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

AU - Abad, P.

AU - Gouzy, J.

AU - Aury, J.M.

AU - Castagnone-Sereno, P.

AU - Danchin, E.G.J.

AU - Deleury, E.

AU - Perfus-Barbeoch, L.

AU - Anthouard, V.

AU - Artiguenave, F.

AU - Blok, V.C.

AU - Caillaud, M.C.

AU - Coutinho, P.M.

AU - Dasilva, C.

AU - De Luca, F.

AU - Deau, F.

AU - Esquibet, M.

AU - Flutre, T.

AU - Goldstone, J.V.

AU - Hamamouch, N.

AU - Hewezi, T.

AU - Jaillon, O.

AU - Jubin, C.

AU - Leonetti, P.

AU - Magliano, M.

AU - Maier, T.R.

AU - Markov, G.V.

AU - McVeigh, Paul

AU - Pesole, G.

AU - Poulain, J.

AU - Robinson-Rechavi, M.

AU - Sallet, E.

AU - Segurens, B.

AU - Steinbach, D.

AU - Tytgat, T.

AU - Ugarte, E.

AU - Van Ghelder, C.

AU - Veronico, P.

AU - Baum, T.J.

AU - Blaxter, M.

AU - Bleve-Zacheo, T.

AU - Davis, E.L.

AU - Ewbank, J.J.

AU - Favery, B.

AU - Grenier, E.

AU - Henrissat, B.

AU - Jones, J.T.

AU - Laudet, V.

AU - Maule, Aaron

AU - Quesneville, H.

AU - Rosso, M.N.

AU - Schiex, T.

AU - Smant, G.

AU - Weissenbach, J.

AU - Wincker, P.

PY - 2008

Y1 - 2008

N2 - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

AB - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

UR - http://www.scopus.com/inward/record.url?scp=49449094873&partnerID=8YFLogxK

U2 - 10.1038/nbt.1482

DO - 10.1038/nbt.1482

M3 - Article

C2 - 18688240

SN - 1087-0156

VL - 26

SP - 909

EP - 915

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 8

ER -

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Abstract

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