Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

P. Abad, J. Gouzy, J.M. Aury, P. Castagnone-Sereno, E.G.J. Danchin, E. Deleury, L. Perfus-Barbeoch, V. Anthouard, F. Artiguenave, V.C. Blok, M.C. Caillaud, P.M. Coutinho, C. Dasilva, F. De Luca, F. Deau, M. Esquibet, T. Flutre, J.V. Goldstone, N. Hamamouch, T. HeweziO. Jaillon, C. Jubin, P. Leonetti, M. Magliano, T.R. Maier, G.V. Markov, Paul McVeigh, G. Pesole, J. Poulain, M. Robinson-Rechavi, E. Sallet, B. Segurens, D. Steinbach, T. Tytgat, E. Ugarte, C. Van Ghelder, P. Veronico, T.J. Baum, M. Blaxter, T. Bleve-Zacheo, E.L. Davis, J.J. Ewbank, B. Favery, E. Grenier, B. Henrissat, J.T. Jones, V. Laudet, Aaron Maule, H. Quesneville, M.N. Rosso, T. Schiex, G. Smant, J. Weissenbach, P. Wincker

Research output: Contribution to journalArticlepeer-review

608 Citations (Scopus)


Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.
Original languageEnglish
Pages (from-to)909-915
Number of pages7
JournalNature Biotechnology
Issue number8
Early online date27 Jul 2008
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Microbiology


Dive into the research topics of 'Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita'. Together they form a unique fingerprint.

Cite this