We used data from 2 global point prevalence surveys of antibiotic prescribing to describe the treatment of sepsis in hospitalized neonates and children. One hundred eighty-five of 824 neonates (22.5%) and 9/786 children (1.1%) received a World Health Organization-recommended first-line treatment; of the remainder, 9/639 neonates (1.4%) and 102/777 children (13.1%) received a World Health Organization-recommended second-line treatment. Reasons for this low adherence to guidance should be explored.
Jackson, C., Hsia, Y., Basmaci, R., Bielicki, J., Heath, P. T., Versporten, A., Goossens, H., & Sharland, M. (2019). Global Divergence From World Health Organization Treatment Guidelines for Neonatal and Pediatric Sepsis. The Pediatric Infectious Disease Journal. https://doi.org/10.1097/inf.0000000000002433