Gold nanoparticles as novel agents for cancer therapy

S Jain; D G Hirst; J M O'Sullivan

doi:10.1259/bjr/59448833

Gold nanoparticles as novel agents for cancer therapy

S Jain, D G Hirst, J M O'Sullivan

Research output: Contribution to journal › Review article › peer-review

861 Citations (Scopus)

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Abstract

Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. In particular, the pre-clinical evidence for gold nanoparticles as sensitisers with ionising radiation in vitro and in vivo at kilovoltage and megavoltage energies is discussed.

Original language	English
Pages (from-to)	101-113
Number of pages	13
Journal	British Journal of Radiology
Volume	85
Issue number	1010
DOIs	https://doi.org/10.1259/bjr/59448833
Publication status	Published - Feb 2012

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Gold nanoparticles as novel agents for cancer therapy",

abstract = "Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. In particular, the pre-clinical evidence for gold nanoparticles as sensitisers with ionising radiation in vitro and in vivo at kilovoltage and megavoltage energies is discussed.",

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year = "2012",

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AU - Jain, S

AU - Hirst, D G

AU - O'Sullivan, J M

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AB - Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. In particular, the pre-clinical evidence for gold nanoparticles as sensitisers with ionising radiation in vitro and in vivo at kilovoltage and megavoltage energies is discussed.

U2 - 10.1259/bjr/59448833

DO - 10.1259/bjr/59448833

M3 - Review article

C2 - 22010024

VL - 85

SP - 101

EP - 113

JO - British Journal of Radiology

JF - British Journal of Radiology

IS - 1010

ER -

Gold nanoparticles as novel agents for cancer therapy

Abstract

ASJC Scopus subject areas

UN SDGs

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