Modernisation has thrown humanity and other forms of life on our planet into a ditch of problems. Poverty, climate change, injustice, and environmental degradation are a few of the shared global problems. The United Nations SDGs are set as the blueprint to achieve a better and more sustainable future for all. The SDGs are well structured to address the global challenges we face including poverty, inequalities, hunger, climate change, environmental degradation, peace and justice. The SDGs have been driven mainly by international donors and ‘professional’ international development organisations. The world is left with 10 years to achieve these ambitious goals and targets. Various reviews indicated that little has been achieving on overall, and the SDGs will not be a reality if a new strategy is not in place to bring inclusion. Microbiology, the scientific discipline of microbes, their effects and practical uses has an insightful influence on our day-to-day living. We present how microbiology and microbiologists could increase the scorecard and accelerate these global goals. Microbiology's contribution to peace, justice, gender equality, decent work and economic growth will be also highlighted among others. The pledge of Leave No One Behind will fast-track progress and microbiology is in a better position to make this work.