Health related quality of life two to five years after gestational diabetes mellitus: Cross-sectional comparative study in the ATLANTIC DIP cohort

Andriy Danyliv, Paddy Gillespie, Ciaran O'Neill, Eoin Noctor, Angela O'Dea, Maire Tierney, Brian E. McGuire, Liam G Glynn, Fidelma Dunne

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)
185 Downloads (Pure)

Abstract

Background
There is no consensus on the effect of gestational diabetes mellitus (GDM) on health-related quality of life (HRQOL) for the mother in the short or long term. In this study we examined HRQOL in a group of women who had GDM in the index pregnancy 2 to 5 years previously and compared it to a group of women with normal glucose tolerance (NGT) in the index pregnancy during the same time period.

Methods
The sample included 234 women who met International Association of Diabetes Study Groups (IADPSG) criteria for GDM in the index pregnancy and 108 who had NGT. The sample was drawn from the ATLATIC-DIP (Diabetes In Pregnancy) cohort – a network of antenatal centers along the Irish Atlantic seaboard serving a population of approximately 500,000 people. HRQOL was measured using the visual analogue component of the EQ-5D-3 L instrument in a cross-sectional survey.

Results
The difference in HRQOL between GDM and NGT groups was not significant when adjusted for the effects of the covariates. HRQOL was negatively affected by increased BMI and abnormal glucose tolerance post-partum in the NGT group. Moderate alcohol consumption was positively associated with HRQOL in the NGT group only. The negative association with smoking on HRQOL was substantially higher in the GDM group.

Conclusions
A diagnosis of GDM does not appear to have an adverse effect on HRQOL, 2 to 5 years after the index pregnancy. On the contrary, its diagnosis might lead to the development of coping strategies, which, consequently attenuates the adverse effect of the subsequent acquisition of abnormal glucose tolerance post-partum on HRQOL. Women whose pregnancy was affected by GDM are more susceptible to the adverse effects on HRQOL of alcohol use and tobacco smoking.

Keywords

Gestational diabetes mellitus Health related quality of life Post-partum Health outcomes
Background
Original languageEnglish
Article number274
Pages (from-to)1-9
JournalBMC Pregnancy and Childbirth
Volume15
Issue number1
DOIs
Publication statusPublished - 2015

Bibliographical note

Export Date: 7 March 2017

Fingerprint

Dive into the research topics of 'Health related quality of life two to five years after gestational diabetes mellitus: Cross-sectional comparative study in the ATLANTIC DIP cohort'. Together they form a unique fingerprint.

Cite this