Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

L.Z. Piao; Y. Li; K.J. Yang; K.A. Park; H.S. Byun; M. Won; J. Hong; J.L. Kim; G.R. Kweon; G.M. Hur; J.H. Seok; J.Y. Cho; T. Chun; D. Hess; R. Sack; S.M. Maira; Derek Brazil; B.A. Hemmings; J. Park

doi:10.1186/1471-2121-10-53

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

L.Z. Piao, Y. Li, K.J. Yang, K.A. Park, H.S. Byun, M. Won, J. Hong, J.L. Kim, G.R. Kweon, G.M. Hur, J.H. Seok, J.Y. Cho, T. Chun, D. Hess, R. Sack, S.M. Maira, Derek Brazil, B.A. Hemmings, J. Park

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Background: The serine/threonine protein kinase B (PKB/Akt) is involved in insulin signaling, cellular survival, and transformation. Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process.

Original language	English
Article number	53
Pages (from-to)	53
Number of pages	1
Journal	BMC Cell Biology
Volume	10
DOIs	https://doi.org/10.1186/1471-2121-10-53
Publication status	Published - 15 Jul 2009

ASJC Scopus subject areas

Cell Biology

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10.1186/1471-2121-10-53

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Piao, L. Z., Li, Y., Yang, K. J., Park, K. A., Byun, H. S., Won, M., Hong, J., Kim, J. L., Kweon, G. R., Hur, G. M., Seok, J. H., Cho, J. Y., Chun, T., Hess, D., Sack, R., Maira, S. M., Brazil, D., Hemmings, B. A., & Park, J. (2009). Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein. BMC Cell Biology, 10, 53. [53]. https://doi.org/10.1186/1471-2121-10-53

Piao, L.Z. ; Li, Y. ; Yang, K.J. ; Park, K.A. ; Byun, H.S. ; Won, M. ; Hong, J. ; Kim, J.L. ; Kweon, G.R. ; Hur, G.M. ; Seok, J.H. ; Cho, J.Y. ; Chun, T. ; Hess, D. ; Sack, R. ; Maira, S.M. ; Brazil, Derek ; Hemmings, B.A. ; Park, J. / Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein. In: BMC Cell Biology. 2009 ; Vol. 10. pp. 53.

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title = "Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein",

abstract = "Background: The serine/threonine protein kinase B (PKB/Akt) is involved in insulin signaling, cellular survival, and transformation. Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process.",

author = "L.Z. Piao and Y. Li and K.J. Yang and K.A. Park and H.S. Byun and M. Won and J. Hong and J.L. Kim and G.R. Kweon and G.M. Hur and J.H. Seok and J.Y. Cho and T. Chun and D. Hess and R. Sack and S.M. Maira and Derek Brazil and B.A. Hemmings and J. Park",

year = "2009",

month = jul,

day = "15",

doi = "10.1186/1471-2121-10-53",

language = "English",

volume = "10",

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Piao, LZ, Li, Y, Yang, KJ, Park, KA, Byun, HS, Won, M, Hong, J, Kim, JL, Kweon, GR, Hur, GM, Seok, JH, Cho, JY, Chun, T, Hess, D, Sack, R, Maira, SM, Brazil, D, Hemmings, BA & Park, J 2009, 'Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein', BMC Cell Biology, vol. 10, 53, pp. 53. https://doi.org/10.1186/1471-2121-10-53

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein. / Piao, L.Z.; Li, Y.; Yang, K.J.; Park, K.A.; Byun, H.S.; Won, M.; Hong, J.; Kim, J.L.; Kweon, G.R.; Hur, G.M.; Seok, J.H.; Cho, J.Y.; Chun, T.; Hess, D.; Sack, R.; Maira, S.M.; Brazil, Derek; Hemmings, B.A.; Park, J.

In: BMC Cell Biology, Vol. 10, 53, 15.07.2009, p. 53.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

AU - Piao, L.Z.

AU - Li, Y.

AU - Yang, K.J.

AU - Park, K.A.

AU - Byun, H.S.

AU - Won, M.

AU - Hong, J.

AU - Kim, J.L.

AU - Kweon, G.R.

AU - Hur, G.M.

AU - Seok, J.H.

AU - Cho, J.Y.

AU - Chun, T.

AU - Hess, D.

AU - Sack, R.

AU - Maira, S.M.

AU - Brazil, Derek

AU - Hemmings, B.A.

AU - Park, J.

PY - 2009/7/15

Y1 - 2009/7/15

N2 - Background: The serine/threonine protein kinase B (PKB/Akt) is involved in insulin signaling, cellular survival, and transformation. Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process.

AB - Background: The serine/threonine protein kinase B (PKB/Akt) is involved in insulin signaling, cellular survival, and transformation. Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. In the present study we investigate novel mechanisms by which CTMP plays a role in apoptosis process.

U2 - 10.1186/1471-2121-10-53

DO - 10.1186/1471-2121-10-53

M3 - Article

VL - 10

SP - 53

JO - BMC Cell Biology

JF - BMC Cell Biology

SN - 1471-2121

M1 - 53

ER -

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

Abstract

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