High-Performance Biosensing Using Arrays of Plasmonic Nanotubes

John McPhillips, Antony Murphy, M.P. Jonsson, William Hendren, Ron Atkinson, F. Hook, Anatoly Zayats, Robert Pollard

Research output: Contribution to journalArticlepeer-review

122 Citations (Scopus)
24 Downloads (Pure)


We show that aligned gold nanotube arrays capable of supporting plasmonic resonances can be used as high performance refractive index sensors in biomolecular binding reactions. A methodology to examine the sensing ability of the inside and outside walls of the nanotube structures is presented. The sensitivity of the plasmonic nanotubes is found to increase as the nanotube walls are exposed, and the sensing characteristic of the inside and outside walls is shown to be different. Finite element simulations showed good qualitative agreement with the observed behavior. Free standing gold nanotubes displayed bulk sensitivities in the region of 250 nm per refractive index unit and a signal-to-noise ratio better than 1000 upon protein binding which is highly competitive with state-of-the-art label-free sensors.
Original languageEnglish
Pages (from-to)2210-2216
Number of pages7
JournalACS Nano
Issue number4
Early online date10 Mar 2010
Publication statusPublished - 27 Apr 2010

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)
  • Physics and Astronomy(all)


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