High salt compatible oxyanion receptors by dual ion imprinting

Sudhirkumar Shinde; Mona Mansour; Anil Incel; Borje Sellergren

doi:10.1039/C9SC06508C

High salt compatible oxyanion receptors by dual ion imprinting

Sudhirkumar Shinde, Mona Mansour, Anil Incel, Borje Sellergren^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

33 Downloads (Pure)

Abstract

The design of hosts for either cations or anions is complicated due to the competition for binding by the host or guest counterions. Imprinting relying on self-assembly offers the possibility to stabilize the guest and its counterion in a favorable geometry. We here report on a comprehensive supramolecular approach to anion receptor design relying on concurrent recognition of both anion and cation. This was achieved by high order complex imprinting of the disodium salt of phenyl-phosphonic acid in combination with neutral urea and sodium ion selective 18-crown-6 monomers. The polymers displayed enhanced affinity for the template or inorganic phosphate or sulfate in competitive aqueous buffers, with affinity and selectivity increasing with increasing ionic strength. The presence of engineered sites for both ionic species dramatically increases the salt uptake in strongly competitive media such as brine.

Original language	English
Pages (from-to)	4246-4250
Journal	Chemical Science
Volume	11
DOIs	https://doi.org/10.1039/C9SC06508C
Publication status	Published - 30 Apr 2020

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10.1039/C9SC06508CLicence: CC BY

High salt compatible oxyanion receptors by dual ion imprinting
Copyright 2020 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 632 KBLicence: CC BY

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AU - Shinde, Sudhirkumar

AU - Mansour, Mona

AU - Incel, Anil

AU - Sellergren, Borje

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Y1 - 2020/4/30

N2 - The design of hosts for either cations or anions is complicated due to the competition for binding by the host or guest counterions. Imprinting relying on self-assembly offers the possibility to stabilize the guest and its counterion in a favorable geometry. We here report on a comprehensive supramolecular approach to anion receptor design relying on concurrent recognition of both anion and cation. This was achieved by high order complex imprinting of the disodium salt of phenyl-phosphonic acid in combination with neutral urea and sodium ion selective 18-crown-6 monomers. The polymers displayed enhanced affinity for the template or inorganic phosphate or sulfate in competitive aqueous buffers, with affinity and selectivity increasing with increasing ionic strength. The presence of engineered sites for both ionic species dramatically increases the salt uptake in strongly competitive media such as brine.

AB - The design of hosts for either cations or anions is complicated due to the competition for binding by the host or guest counterions. Imprinting relying on self-assembly offers the possibility to stabilize the guest and its counterion in a favorable geometry. We here report on a comprehensive supramolecular approach to anion receptor design relying on concurrent recognition of both anion and cation. This was achieved by high order complex imprinting of the disodium salt of phenyl-phosphonic acid in combination with neutral urea and sodium ion selective 18-crown-6 monomers. The polymers displayed enhanced affinity for the template or inorganic phosphate or sulfate in competitive aqueous buffers, with affinity and selectivity increasing with increasing ionic strength. The presence of engineered sites for both ionic species dramatically increases the salt uptake in strongly competitive media such as brine.

U2 - 10.1039/C9SC06508C

DO - 10.1039/C9SC06508C

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VL - 11

SP - 4246

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JO - Chemical Science

JF - Chemical Science

SN - 2041-6520

ER -

High salt compatible oxyanion receptors by dual ion imprinting

Abstract

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