TY - JOUR
T1 - Highly Selective Reduction of α, β-Unsaturated Aldehydes and Ketones under Ambient Conditions using Tetraalkylphosphonium-based Ionic Liquids
AU - Manyar, Haresh
AU - Ralphs, Kathryn
AU - McCourt, Éadaoin
AU - Nockemann, Peter
AU - Jacquemin, Johan
PY - 2018/11/9
Y1 - 2018/11/9
N2 - An efficient and green protocol for highly selective reduction of α,-unsaturated aldehydes and ketones at room temperature is described in a range of ionic liquids, in the absence of noble metal catalysts, by using NaBH4 as reducing agent. Most notably, using [P6,6,6,14][N(CN)2] ionic liquid, in absence of organic solvent, within 10 min, 97% conversion of cinnamaldehyde was achieved with 100% selectivity towards cinnamyl alcohol. The ionic liquid was easily recycled without any noticeable decline in activity. The reduction protocol was further extended to a variety of α,-unsaturated aldehydes and ketones.
AB - An efficient and green protocol for highly selective reduction of α,-unsaturated aldehydes and ketones at room temperature is described in a range of ionic liquids, in the absence of noble metal catalysts, by using NaBH4 as reducing agent. Most notably, using [P6,6,6,14][N(CN)2] ionic liquid, in absence of organic solvent, within 10 min, 97% conversion of cinnamaldehyde was achieved with 100% selectivity towards cinnamyl alcohol. The ionic liquid was easily recycled without any noticeable decline in activity. The reduction protocol was further extended to a variety of α,-unsaturated aldehydes and ketones.
U2 - 10.1002/slct.201801092
DO - 10.1002/slct.201801092
M3 - Article
SN - 2365-6549
JO - ChemistrySelect
JF - ChemistrySelect
ER -