Histopathologists’ approach to keratoacanthoma: a multisite survey of regional variation in Great Britain and Ireland

Richard A Carr, Joseph P Houghton

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18 Citations (Scopus)

Abstract

Introduction: This survey examines regional variation in the diagnosis of keratoacanthoma (KA).

Methods: Twenty-three departments from Great Britain and Ireland were invited. The number of cases coded as KA or cutaneous SCC in the previous 12 months was retrieved. An SCC: KA ratio was calculated. Participants also provided free text responses.

Results: Seventeen departments replied. A total of 11 718 cases were included with a breakdown of 998 KA and 10 720 SCC. The mean SCC:KA ratio was 10.7:1, range (2.5:1 to 139:1). Free text responses are presented.

Discussions: An extreme variation in approach is highlighted by this survey. We believe a multidisciplinary team approach to the diagnosis of KA is essential. There seems to be a need for a carefully considered clinicopathological study, backed up by molecular studies, to better understand the natural biology of this diagnosis.
Original languageEnglish
Pages (from-to)637-638
Number of pages2
JournalJournal of Clinical Pathology
Volume67
Issue number7
Early online date24 Apr 2014
DOIs
Publication statusPublished - Jul 2014

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