Home-based Perimetry for Glaucoma: Where are We Now?

Qëndresë Daka, Rona Mustafa, Burim Neziri, Gianni Virgili, Augusto Azuara-Blanco

Research output: Contribution to journalArticlepeer-review

Abstract

To systematically summarize the current literature on home-based perimeters for glaucoma. Systematic review was conducted in accordance with PRISMA-DTA checklist. Studies reporting portable perimeters designed for home use were retrieved from electronic databases and hand search of reference lists of relevant publications. Studies reporting diagnostic accuracy data were evaluated with QUADAS-2 tool and using standard automated perimetry (SAP) as reference standard. Other aspects of the technology such as detection of disease progression and patient acceptability were also included. Data were reported in narrative and tabular form. Out of 18 included studies, 10 evaluated tablet-based perimeters, 4 evaluated web-based perimeters and 4 evaluated head-mounted displays. Most studies used a clinic or laboratory setting. All studies reporting diagnostic accuracy data had high risk of bias in at least one domain. Across studies, sensitivity ranged from 54% in detecting mild to 91% in detecting moderate/severe glaucoma patients from controls while specificity was between 50-100% for any form of glaucoma. Reported acceptability was high but had high risk of bias. Several promising technologies designed for home-based perimetry have been reported. Current studies used a controlled setting in highly selected populations. There is uncertainty on the performance and value of home-perimetry for glaucoma. Additional efforts are required to elucidate the ability of the home-based perimeters to detect glaucoma and disease progression in real life situations.
Original languageEnglish
JournalJournal of glaucoma
Early online date25 Mar 2022
DOIs
Publication statusEarly online date - 25 Mar 2022

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