Hydrogels as drug-delivery platforms: Physicochemical barriers and solutions

L.B. Alkayyali, O.A. Abu-Diak, G.P. Andrews, D.S. Jones

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The properties of hydrogels, in particular their high biocompatibility and water sorption uptake, make hydrogels very attractive in drug delivery and biomedical devices. These favorable features of hydrogels are compromised by certain structural limitations such as those associated with their low mechanical strength in the swollen state. This review highlights the most important challenges that may seriously affect the practical implementation of hydrogels in clinical practice and the solutions that may be applied to overcome these limitations.
Original languageEnglish
Pages (from-to)775-786
Number of pages12
JournalTherapeutic Delivery
Issue number6
Publication statusPublished - 01 Jun 2012

ASJC Scopus subject areas

  • Pharmaceutical Science


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