Abstract
Background: Hypercapnic acidosis exerts protective effects in acute lung injury but may also slow cellular repair. These effects may be mediated via inhibition of nuclear factor-kappa B (NF-kappa B), a pivotal transcriptional regulator in inflammation and repair.
Original language | English |
---|---|
Pages (from-to) | 976-982 |
Number of pages | 7 |
Journal | Thorax |
Volume | 64 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2009 |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine