IL-15 in autoimmunity and cancer O-tu-b or not O-tu-b?

Paul N. Moynagh

doi:10.1038/s41590-019-0424-z

IL-15 in autoimmunity and cancer O-tu-b or not O-tu-b?

Paul N. Moynagh^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › peer-review

3 Citations (Scopus)

Abstract

The cytokine IL-15 controls the homeostasis and activation of CD8⁺ T cells and natural killer cells. A new study reveals the deubiquitinase Otub1 to be a negative regulator of IL-15 signaling, with important consequences for autoimmunity and anti-cancer immunity.

Original language	English
Pages (from-to)	780-782
Number of pages	3
Journal	Nature Immunology
Volume	20
Issue number	7
DOIs	https://doi.org/10.1038/s41590-019-0424-z
Publication status	Published - 10 Jun 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1038/s41590-019-0424-zLicence: Unspecified

Cite this

@article{e63580b6f3064c31bd2475bcffa8a4b7,

title = "IL-15 in autoimmunity and cancer O-tu-b or not O-tu-b?",

abstract = "The cytokine IL-15 controls the homeostasis and activation of CD8+ T cells and natural killer cells. A new study reveals the deubiquitinase Otub1 to be a negative regulator of IL-15 signaling, with important consequences for autoimmunity and anti-cancer immunity.",

author = "Moynagh, \{Paul N.\}",

year = "2019",

month = jun,

day = "10",

doi = "10.1038/s41590-019-0424-z",

language = "English",

volume = "20",

pages = "780--782",

journal = "Nature Immunology",

issn = "1529-2908",