Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability

María Teresa García-Conesa; Rocío García-Villalba; María Dolores Frutos-Lisón; Carlos Javier García; Javier Marhuenda; Pilar Zafrilla; Juan Antonio Tudela; Marta Ruiz Arráez; Gary Williamson; Carrie Ruxton; Francisco A. Tomás-Barberán

doi:10.1039/d5fo04536c

Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability

María Teresa García-Conesa
, Rocío García-Villalba
, María Dolores Frutos-Lisón
, Carlos Javier García
, Javier Marhuenda
, Pilar Zafrilla
, Juan Antonio Tudela
, Marta Ruiz Arráez
, Gary Williamson
, Carrie Ruxton
, Francisco A. Tomás-Barberán

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

30 Downloads (Pure)

Abstract

The impact of fruit juices on postprandial glucose response (PPGR) remains controversial due to their free sugar content; while the fruit matrix helps attenuate this response, the effect varies widely among individuals.

Original language	English
Pages (from-to)	2292-2310
Number of pages	19
Journal	Food and Function
Volume	17
Issue number	5
Early online date	11 Feb 2026
DOIs	https://doi.org/10.1039/d5fo04536c
Publication status	Published - 09 Mar 2026

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10.1039/d5fo04536cLicence: CC BY-NC

Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability
Copyright 2026 the authors. This is an open access Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction for non-commercial purposes, provided the author and source are cited.
Final published version, 2.29 MBLicence: CC BY-NC

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García-Conesa, M. T., García-Villalba, R., Frutos-Lisón, M. D., García, C. J., Marhuenda, J., Zafrilla, P., Tudela, J. A., Arráez, M. R., Williamson, G., Ruxton, C., & Tomás-Barberán, F. A. (2026). Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability. Food and Function, 17(5), 2292-2310. https://doi.org/10.1039/d5fo04536c

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title = "Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability",

abstract = "The impact of fruit juices on postprandial glucose response (PPGR) remains controversial due to their free sugar content; while the fruit matrix helps attenuate this response, the effect varies widely among individuals.",

author = "Garc{\'i}a-Conesa, \{Mar{\'i}a Teresa\} and Roc{\'i}o Garc{\'i}a-Villalba and Frutos-Lis{\'o}n, \{Mar{\'i}a Dolores\} and Garc{\'i}a, \{Carlos Javier\} and Javier Marhuenda and Pilar Zafrilla and Tudela, \{Juan Antonio\} and Arr{\'a}ez, \{Marta Ruiz\} and Gary Williamson and Carrie Ruxton and Tom{\'a}s-Barber{\'a}n, \{Francisco A.\}",

year = "2026",

month = mar,

day = "9",

doi = "10.1039/d5fo04536c",

language = "English",

volume = "17",

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García-Conesa, MT, García-Villalba, R, Frutos-Lisón, MD, García, CJ, Marhuenda, J, Zafrilla, P, Tudela, JA, Arráez, MR, Williamson, G, Ruxton, C & Tomás-Barberán, FA 2026, 'Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability', Food and Function, vol. 17, no. 5, pp. 2292-2310. https://doi.org/10.1039/d5fo04536c

Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability. / García-Conesa, María Teresa; García-Villalba, Rocío; Frutos-Lisón, María Dolores et al.
In: Food and Function, Vol. 17, No. 5, 09.03.2026, p. 2292-2310.

Research output: Contribution to journal › Article › peer-review

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T1 - Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability

AU - García-Conesa, María Teresa

AU - García-Villalba, Rocío

AU - Frutos-Lisón, María Dolores

AU - García, Carlos Javier

AU - Marhuenda, Javier

AU - Zafrilla, Pilar

AU - Tudela, Juan Antonio

AU - Arráez, Marta Ruiz

AU - Williamson, Gary

AU - Ruxton, Carrie

AU - Tomás-Barberán, Francisco A.

PY - 2026/3/9

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N2 - The impact of fruit juices on postprandial glucose response (PPGR) remains controversial due to their free sugar content; while the fruit matrix helps attenuate this response, the effect varies widely among individuals.

AB - The impact of fruit juices on postprandial glucose response (PPGR) remains controversial due to their free sugar content; while the fruit matrix helps attenuate this response, the effect varies widely among individuals.

U2 - 10.1039/d5fo04536c

DO - 10.1039/d5fo04536c

M3 - Article

SN - 2042-6496

VL - 17

SP - 2292

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JO - Food and Function

JF - Food and Function

IS - 5

ER -

Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability

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