Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases

Essyrose  Mathew; Sarah A. Stewart; Emilia Utomo; Eneko Larrañeta; Dimitrios A. Lamprou

doi:10.1016/B978-0-12-821749-8.00003-3

Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases

Essyrose Mathew, Sarah A. Stewart, Emilia Utomo, Eneko Larrañeta, Dimitrios A. Lamprou^*

^*Corresponding author for this work

School of Pharmacy

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

1 Citation (Scopus)

Abstract

Implantable and long-lasting drug delivery systems provide sustained delivery of drug over a period of weeks to months. These systems can provide many advantages in the delivery of drugs for conditions in which the patient is required to take medications frequently for an indefinite period of time, such as less frequent dosing and improved quality of life. This chapter will cover infectious, inflammatory, endocrine and neurodegenerative diseases. In the majority of these diseases, frequent dosing is required by the patient leading to poor adherence by patients. Therefore, long acting implants and systems are evaluated as novel methods for drug delivery, which can reduce dosing frequency and improve patient adherence, in turn improving efficacy of treatment.

Original language	English
Title of host publication	Long acting drug delivery systems
Editors	Eneko Larrañeta, Thakur Raghu Raj Singh , Ryan F. Donnelly
Publisher	Elsevier
Chapter	8
Pages	223-248
ISBN (Print)	9780128217498
DOIs	https://doi.org/10.1016/B978-0-12-821749-8.00003-3
Publication status	Published - 01 Dec 2021

Publication series

Name	Woodhead Publishing Series in Biomaterials

Keywords

3D Printing
Nanoparticles
PLGA
Implantable
Drug Delivery Systems
Infectious Diseases
Inflammatory
Endocrine
Neurodegenerative

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-821749-8.00003-3Licence: Unspecified

Novel systems for transdermal and intradermal drug delivery
Mathew, E. (Author), Lamprou, D. (Supervisor), Donnelly, R. (Supervisor) & Larraneta Landa, E. (Supervisor), Jul 2023
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

Mathew, E., Stewart, S. A., Utomo, E., Larrañeta, E., & Lamprou, D. A. (2021). Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases. In E. Larrañeta, T. R. R. Singh , & R. F. Donnelly (Eds.), Long acting drug delivery systems (pp. 223-248). (Woodhead Publishing Series in Biomaterials). Elsevier. https://doi.org/10.1016/B978-0-12-821749-8.00003-3

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keywords = "3D Printing, Nanoparticles, PLGA, Implantable, Drug Delivery Systems, Infectious Diseases, Inflammatory, Endocrine, Neurodegenerative",

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Mathew, E, Stewart, SA, Utomo, E, Larrañeta, E & Lamprou, DA 2021, Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases. in E Larrañeta, TRR Singh & RF Donnelly (eds), Long acting drug delivery systems. Woodhead Publishing Series in Biomaterials, Elsevier, pp. 223-248. https://doi.org/10.1016/B978-0-12-821749-8.00003-3

Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases. / Mathew, Essyrose ; Stewart, Sarah A.; Utomo, Emilia et al.
Long acting drug delivery systems. ed. / Eneko Larrañeta; Thakur Raghu Raj Singh ; Ryan F. Donnelly. Elsevier, 2021. p. 223-248 (Woodhead Publishing Series in Biomaterials).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

TY - CHAP

T1 - Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases

AU - Mathew, Essyrose

AU - Stewart, Sarah A.

AU - Utomo, Emilia

AU - Larrañeta, Eneko

AU - Lamprou, Dimitrios A.

PY - 2021/12/1

Y1 - 2021/12/1

N2 - Implantable and long-lasting drug delivery systems provide sustained delivery of drug over a period of weeks to months. These systems can provide many advantages in the delivery of drugs for conditions in which the patient is required to take medications frequently for an indefinite period of time, such as less frequent dosing and improved quality of life. This chapter will cover infectious, inflammatory, endocrine and neurodegenerative diseases. In the majority of these diseases, frequent dosing is required by the patient leading to poor adherence by patients. Therefore, long acting implants and systems are evaluated as novel methods for drug delivery, which can reduce dosing frequency and improve patient adherence, in turn improving efficacy of treatment.

AB - Implantable and long-lasting drug delivery systems provide sustained delivery of drug over a period of weeks to months. These systems can provide many advantages in the delivery of drugs for conditions in which the patient is required to take medications frequently for an indefinite period of time, such as less frequent dosing and improved quality of life. This chapter will cover infectious, inflammatory, endocrine and neurodegenerative diseases. In the majority of these diseases, frequent dosing is required by the patient leading to poor adherence by patients. Therefore, long acting implants and systems are evaluated as novel methods for drug delivery, which can reduce dosing frequency and improve patient adherence, in turn improving efficacy of treatment.

KW - 3D Printing

KW - Nanoparticles

KW - PLGA

KW - Implantable

KW - Drug Delivery Systems

KW - Infectious Diseases

KW - Inflammatory

KW - Endocrine

KW - Neurodegenerative

U2 - 10.1016/B978-0-12-821749-8.00003-3

DO - 10.1016/B978-0-12-821749-8.00003-3

M3 - Chapter (peer-reviewed)

SN - 9780128217498

T3 - Woodhead Publishing Series in Biomaterials

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BT - Long acting drug delivery systems

A2 - Larrañeta, Eneko

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ER -

Mathew E, Stewart SA, Utomo E, Larrañeta E , Lamprou DA. Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases. In Larrañeta E, Singh TRR, Donnelly RF, editors, Long acting drug delivery systems. Elsevier. 2021. p. 223-248. (Woodhead Publishing Series in Biomaterials). Epub 2021 Oct 1. doi: 10.1016/B978-0-12-821749-8.00003-3

Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases

Abstract

Publication series

Keywords

UN SDGs

Access to Document

Fingerprint

Student theses

Novel systems for transdermal and intradermal drug delivery

Cite this