Implementation of personalised medicine policies in mental healthcare: results from a stated preference study in the UK

Alan J. McMichael, Joseph P. M. Kane*, Jonathan J. Rolison, Francis A. O'Neill, Marco Boeri, Frank Kee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
54 Downloads (Pure)

Abstract

Background
Public support for the implementation of personalised medicine policies (PMPs) within routine care is important owing to the high financial costs involved and the potential for redirection of resources from other services.

Aims
We aimed to determine the attributes of a PMP most likely to elicit public support for implementation. We also aimed to determine whether such support differed between a depression PMP and one for cystic fibrosis.

Method
In a discrete-choice experiment, paired vignettes illustrating both the current model of care (CMoC) and a hypothetical PMP for either depression or cystic fibrosis were presented to a representative sample of the UK public (n = 2804). Each vignette integrated varying attributes, including anticipated therapeutic benefit over CMoC, and the annual cost to the taxpayer. Respondents were invited to express their preference for either the PMP or CMoC within each pair.

Results
The financial cost was the most important attribute influencing public support for PMPs. Respondents favoured PMP implementation where it benefited a higher proportion of patients or was anticipated to be more effective than CMoC. A reduction in services for non-eligible patients reduced the likelihood of support for PMPs. Respondents were more willing to fund PMPs for cystic fibrosis than for depression.

Conclusions
Cost is a significant factor in the public's support for PMPs, but essential caveats, such as protection for services available to PMP-ineligible patients, may also apply. Further research should explore the factors contributing to condition-specific nuances in public support for PMPs.
Original languageEnglish
Article numbere40
Number of pages7
JournalBJPsych Open
Volume8
Issue number2
DOIs
Publication statusPublished - 03 Feb 2022

Fingerprint

Dive into the research topics of 'Implementation of personalised medicine policies in mental healthcare: results from a stated preference study in the UK'. Together they form a unique fingerprint.

Cite this