Implications of between-isolate variation for climate change impact modelling of Haemonchus contortus populations

Hannah Rose Vineer, Jasmin Steiner, Friederike Knapp-Lawitzke, Katie Bull, Elke von Son-de Fernex, Antonio Bosco, Hubertus Hertzberg, Janina Demeler, Laura Rinaldi, Alison Morrison, Philip Skuce, Dave Bartley, Eric Morgan

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Abstract

The impact of climate change on parasites and parasitic diseases is a growing concern and numerous empirical and mechanistic models have been developed to predict climate-driven spatial and temporal changes in the distribution of parasites and disease risk. Variation in parasite phenotype and life-history traits between isolates could undermine the application of such models at broad spatial scales. Seasonal variation in the transmission of the haematophagous gastrointestinal nematode Haemonchus contortus, one of the most pathogenic helminth species infecting sheep and goats worldwide, is primarily determined by the impact of environmental conditions on the free-living stages. To evaluate variability in the development success and mortality of the free-living stages of H. contortus and the impact of this variability on future climate impact modelling, three isolates of diverse origin were cultured at a range of temperatures between 15 °C and 37 °C to determine their development success compared with simulations using the GLOWORM-FL H. contortus model. No significant difference was observed in the developmental success of the three isolates of H. contortus tested, nor between isolates and model simulations. However, development success of all isolates at 37 °C was lower than predicted by the model, suggesting the potential for overestimation of transmission risk at higher temperatures, such as those predicted under some scenarios of climate change. Recommendations are made for future climate impact modelling of gastrointestinal nematodes.
Original languageEnglish
Pages (from-to)144-149
Number of pages6
JournalVeterinary Parasitology
Volume229
Early online date17 Oct 2016
DOIs
Publication statusEarly online date - 17 Oct 2016

Keywords

  • Haemonchus contortus, Gastrointestinal nematode, Trait variation, Local adaptation, Development success, Climate impact modelling, Temperature

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  • Cite this

    Rose Vineer, H., Steiner, J., Knapp-Lawitzke, F., Bull, K., von Son-de Fernex, E., Bosco, A., Hertzberg, H., Demeler, J., Rinaldi, L., Morrison, A., Skuce, P., Bartley, D., & Morgan, E. (2016). Implications of between-isolate variation for climate change impact modelling of Haemonchus contortus populations. Veterinary Parasitology, 229, 144-149. https://doi.org/10.1016/j.vetpar.2016.10.015