Improved synthesis of 4,4′-diamino-2,2′-bipyridine from 4,4′-dinitro-2,2′-bipyridine-N,N′-dioxide

Paul Kavanagh, Dónal Leech*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)


A superior synthetic route to 4,4′-diamino-2,2′-bipyridine has been developed. This procedure compares favorably with existing methods, producing 4 times the yield previously reported. In addition, mild reaction conditions are utilized, allowing a considerably more efficient production, and subsequent purification, of the diamino complex.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalTetrahedron Letters
Issue number1
Publication statusPublished - 01 Jan 2004
Externally publishedYes


  • Diamino
  • Electron donor
  • Reduction
  • Substituted bipyridine

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery


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