Improved synthesis of 4,4′-diamino-2,2′-bipyridine from 4,4′-dinitro-2,2′-bipyridine-N,N′-dioxide

Paul Kavanagh; Dónal Leech

doi:10.1016/j.tetlet.2003.10.096

Improved synthesis of 4,4′-diamino-2,2′-bipyridine from 4,4′-dinitro-2,2′-bipyridine-N,N′-dioxide

Paul Kavanagh, Dónal Leech^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

A superior synthetic route to 4,4′-diamino-2,2′-bipyridine has been developed. This procedure compares favorably with existing methods, producing 4 times the yield previously reported. In addition, mild reaction conditions are utilized, allowing a considerably more efficient production, and subsequent purification, of the diamino complex.

Original language	English
Pages (from-to)	121-123
Number of pages	3
Journal	Tetrahedron Letters
Volume	45
Issue number	1
DOIs	https://doi.org/10.1016/j.tetlet.2003.10.096
Publication status	Published - 01 Jan 2004
Externally published	Yes

Keywords

Diamino
Electron donor
Reduction
Substituted bipyridine

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/j.tetlet.2003.10.096

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abstract = "A superior synthetic route to 4,4′-diamino-2,2′-bipyridine has been developed. This procedure compares favorably with existing methods, producing 4 times the yield previously reported. In addition, mild reaction conditions are utilized, allowing a considerably more efficient production, and subsequent purification, of the diamino complex.",

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AU - Leech, Dónal

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N2 - A superior synthetic route to 4,4′-diamino-2,2′-bipyridine has been developed. This procedure compares favorably with existing methods, producing 4 times the yield previously reported. In addition, mild reaction conditions are utilized, allowing a considerably more efficient production, and subsequent purification, of the diamino complex.

AB - A superior synthetic route to 4,4′-diamino-2,2′-bipyridine has been developed. This procedure compares favorably with existing methods, producing 4 times the yield previously reported. In addition, mild reaction conditions are utilized, allowing a considerably more efficient production, and subsequent purification, of the diamino complex.

KW - Diamino

KW - Electron donor

KW - Reduction

KW - Substituted bipyridine

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Improved synthesis of 4,4′-diamino-2,2′-bipyridine from 4,4′-dinitro-2,2′-bipyridine-N,N′-dioxide

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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