Improved synthesis of tadalafil using dimethyl carbonate and ionic liquids

Martyn J. Earle*, Marco Noè, Alvise Perosa, Kenneth R. Seddon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

An improved synthesis of tadalafil, a drug for the treatment of male erectile dysfunction, involves the use of safer solvents and reagents as well as a reduced number of steps.

Original languageEnglish
Pages (from-to)1204-1211
Number of pages8
JournalRSC Advances
Volume4
Issue number3
Early online date15 Nov 2013
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

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