In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects

F. Diel, M. Detscher, Bettina Schock, Madeleine Ennis

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Synthetic pyrethroids are increasingly used as insecticides and marketed as having relatively low human toxicity. The aim of this study was to examine the in vitro effects of the synthetic pyrethroid S-bioallethrin on human blood lymphocytes and basophils in atopic individuals and nonatopic control subjects. S-bioallethrin caused inhibition of lymphocyte proliferation after a 72-h culture period in a concentration-dependent manner. The inhibition of the lymphocyte proliferation by S-bioallethrin at the concentration 6.5 mu M correlated well with the total serum IgE values (r= -0.89, P
Original languageEnglish
Pages (from-to)1052-1059
Number of pages8
JournalAllergy
Volume53
Issue number11
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Immunology

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