Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance

Tracy Robson; M.E. Price; M.L. Moore; M.C. Joiner; V.J. McKelvey-Martin; S.R. McKeown; David Hirst

Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance

Tracy Robson, M.E. Price, M.L. Moore, M.C. Joiner, V.J. McKelvey-Martin, S.R. McKeown, David Hirst

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).

Original language	English
Pages (from-to)	617-623
Number of pages	7
Journal	International journal of radiation biology
Volume	76
Issue number	5
Publication status	Published - 2000

ASJC Scopus subject areas

Agricultural and Biological Sciences (miscellaneous)
Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology
Nuclear Energy and Engineering
Radiation

Cite this

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title = "Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance",

abstract = "Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).",

author = "Tracy Robson and M.E. Price and M.L. Moore and M.C. Joiner and V.J. McKelvey-Martin and S.R. McKeown and David Hirst",

year = "2000",

language = "English",

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journal = "International journal of radiation biology",

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T1 - Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance

AU - Robson, Tracy

AU - Price, M.E.

AU - Moore, M.L.

AU - Joiner, M.C.

AU - McKelvey-Martin, V.J.

AU - McKeown, S.R.

AU - Hirst, David

PY - 2000

Y1 - 2000

N2 - Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).

AB - Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).

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M3 - Article

VL - 76

SP - 617

EP - 623

JO - International journal of radiation biology

JF - International journal of radiation biology

IS - 5

ER -

Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance

Abstract

ASJC Scopus subject areas

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