Purpose: To determine whether repression of a recently isolated, X-ray-responsive gene, DIR1, using antisense oligonucleotides could affect clonogenic cell survival and repair of DNA strand breaks and have a possible role in the mechanism underlying the phenomenon of 'induced radioresistance' (IRR).
|Number of pages||7|
|Journal||International journal of radiation biology|
|Publication status||Published - 2000|
ASJC Scopus subject areas
- Agricultural and Biological Sciences (miscellaneous)
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
- Nuclear Energy and Engineering
Robson, T., Price, M. E., Moore, M. L., Joiner, M. C., McKelvey-Martin, V. J., McKeown, S. R., & Hirst, D. (2000). Increased repair and cell survival in cells treated with DIR1 antisense oligonucleotides: implications for induced radioresistance. International journal of radiation biology, 76(5), 617-623.