Kallistatin, a serpin widely produced throughout the body, has vasodilatory, anti-angiogenic, anti-oxidant, and anti-inflammatory effects. Effects of diabetes and its vascular complications on serum kallistatin levels are unknown.
Jenkins, A. J., McBride, J. D., Januszewski, A. S., Karschimkus, C. S., Zhang, B., O'Neal, D. N., Nelson, C. L., Chung, J. S., Harper, C. A., Lyons, T. J., & Ma, J-X. (2010). Increased serum kallistatin levels in type 1 diabetes patients with vascular complications. Journal of angiogenesis research, 2, 19. https://doi.org/10.1186/2040-2384-2-19