Influence of maternal diabetes mellitus on fetal iron status

A.M. Verner, J. Manderson, Terence Lappin, David R McCance, H Halliday, David Sweet

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

OBJECTIVE: To determine the effects of maternal diabetes on fetal iron status using serum transferrin receptors (STfR) and their ratio to ferritin (TfR-F index) in cord blood. METHODS: Iron, ferritin, erythropoietin, STfR and haemoglobin concentration were measured and TfR-F index calculated in 97 maternal/cord blood pairs. Forty-nine women had type 1 diabetes (diagnosed before pregnancy) and these were compared with forty-eight non- diabetic controls. The women with type 1 diabetes were recruited consecutively from attendance at the joint antenatal endocrine clinic while the control group of women was recruited from consecutive attendance at the remaining antenatal clinics. RESULTS: The infants of the diabetic women had significantly lower levels of ferritin (47 vs 169 mug/l; p
Original languageEnglish
Pages (from-to)399-401
Number of pages3
JournalArch Dis Child Fetal Neonatal Ed.
Volume92(5)
Issue number5
Publication statusPublished - Sep 2007

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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