Influence of progressive renal dysfunction in chronic heart failure

Hean Y Ong, D Paul Nicholls, Alexander Maxwell

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Chronic heart failure (CHF) is often associated with impaired renal function due to hypoperfusion. Such patients are very sensitive to changes in renal perfusion pressure, and may develop acute tubular necrosis if the pressure falls too far. The situation is complicated by the use of diuretics, ACE inhibitors and spironolactone, all of which may affect renal function and potassium balance. Chronic renal failure (CRF) may also be associated with fluid overload. Anaemia and hypertension in CRF contribute to the development of left ventricular hypertrophy (LVH), which carries a poor prognosis, so correction of these factors is important.
Original languageEnglish
Pages (from-to)125-30
Number of pages6
JournalEuropean Journal of Heart Failure
Issue number2
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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