Abstract
Translational research aims to provide direct support for advancing novel treatment approaches in oncology towards improving patient outcomes. Preclinical studies have a central role in this process and the ability to accurately model biological and physical aspects of the clinical scenario in radiation oncology is critical to translational success. The use of small animal irradiators with disease relevant mouse models and advanced in vivo imaging approaches offers unique possibilities to interrogate the radiotherapy response of tumors and normal tissues with high potential to translate to improvements in clinical outcomes. The present review highlights the current technology and applications of small animal irradiators, and explores how these can be combined with molecular and functional imaging in advanced preclinical radiotherapy research.
Original language | English |
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Journal | Cancers |
Volume | 11 |
Issue number | 2 |
DOIs | |
Publication status | Published - 02 Feb 2019 |
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Dive into the research topics of 'Integrating Small Animal Irradiators with Functional Imaging for Advanced Preclinical Radiotherapy Research.'. Together they form a unique fingerprint.Student Theses
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Refinement of soft tissue targeting and alignment protocols in small animal radiotherapy using an injectable fiducial marker
Author: Brown, K., Jul 2022Supervisor: Butterworth, K. (Supervisor) & Prise, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
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