Intensity-modulated radiotherapy reduces lung irradiation in patients with carcinoma of the oesophagus.

C.M. Nutting, J.L. Bedford, V Cosgrove, D.M. Tait, D.P. Dearnaley, S. Webb

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The 2-year survival rate after conventional radiotherapy for carcinoma of the oesophagus is around 10–20% [8]. Concomitant chemoradiation schedules have produced survival figures of 25–30% at 5 years, and this is now considered standard treatment [1]. Conformal radiotherapy techniques offer the potential to deliver higher doses of radiation to oesophageal tumours [5], and this may improve local tumour control. However, concerns regarding late normal tissue damage to the lung parenchyma and spinal cord remain a concern. Intensitymodulated radiotherapy (IMRT) allows complex dose distributions to be produced, and can reduce the dose to radiosensitive organs close to the tumour [2]. The present study was designed to investigate the impact of beam intensity modulation on treatment planning for carcinoma of the oesophagus, by comparing a standard three-dimensional conformal radiotherapy (3DCRT) technique to an IMRT technique using the same number and orientation of treatment fields.
Original languageEnglish
Pages (from-to)128-131
Number of pages4
JournalFrontiers of Radiation Therapy and Oncology
Volume37
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Radiology Nuclear Medicine and imaging

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