The 2-year survival rate after conventional radiotherapy for carcinoma of the oesophagus is around 10–20% . Concomitant chemoradiation schedules have produced survival figures of 25–30% at 5 years, and this is now considered standard treatment . Conformal radiotherapy techniques offer the potential to deliver higher doses of radiation to oesophageal tumours , and this may improve local tumour control. However, concerns regarding late normal tissue damage to the lung parenchyma and spinal cord remain a concern. Intensitymodulated radiotherapy (IMRT) allows complex dose distributions to be produced, and can reduce the dose to radiosensitive organs close to the tumour . The present study was designed to investigate the impact of beam intensity modulation on treatment planning for carcinoma of the oesophagus, by comparing a standard three-dimensional conformal radiotherapy (3DCRT) technique to an IMRT technique using the same number and orientation of treatment fields.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging