Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up

Vittoria Murro; Dario Pasquale Mucciolo; Dario Giorgio; Andrea Sodi; Federica Boraldi; Daniela Quaglino; Gianni Virgili; Stanislao Rizzo

doi:10.1080/13816810.2019.1666882

Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up

Vittoria Murro, Dario Pasquale Mucciolo^*, Dario Giorgio, Andrea Sodi, Federica Boraldi, Daniela Quaglino, Gianni Virgili, Stanislao Rizzo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Purposes: To describe the long-term follow-up of a patient affected by Pseudoxanthoma Elasticum (PXE) and acquired macular vitelliform lesions in both eyes. Material and methods: Case report Results: We reported the 9-year follow-up of a patient affected by PXE. We described the onset and the resolution of the vitelliform macular lesions which lasted 5 years. The vitelliform lesion appeared almost simultaneously in both eyes with an initial increase in size, even though asymmetrical. We detected the intraretinal migration of hyper-reflective foci in both eyes during the follow-up. Choroidal neovascularization (CNV) occurred in her right eye during the follow-up. Visual acuity decreased from 20/20 to 20/32 in left eye; from 20/20 to 20/100 in her right eye. Conclusions: we reported the natural history of acquired vitelliform lesion in PXE-related retinopathy describing the Intraretinal hyperreflective foci migration.

Original language	English
Pages (from-to)	385-387
Number of pages	3
Journal	Ophthalmic genetics
Volume	40
Issue number	4
DOIs	https://doi.org/10.1080/13816810.2019.1666882
Publication status	Published - 21 Sep 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2019, © 2019 Taylor & Francis Group, LLC.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

acquired vitelliform lesion
CNV
hyper-reflective foci
pigment migration
pseudoxantoma elasticum
PXE

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology
Genetics(clinical)

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10.1080/13816810.2019.1666882Licence: Unspecified

Cite this

@article{941fd2584f084aecbf33f1780dd40513,

title = "Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up",

abstract = "Purposes: To describe the long-term follow-up of a patient affected by Pseudoxanthoma Elasticum (PXE) and acquired macular vitelliform lesions in both eyes. Material and methods: Case report Results: We reported the 9-year follow-up of a patient affected by PXE. We described the onset and the resolution of the vitelliform macular lesions which lasted 5 years. The vitelliform lesion appeared almost simultaneously in both eyes with an initial increase in size, even though asymmetrical. We detected the intraretinal migration of hyper-reflective foci in both eyes during the follow-up. Choroidal neovascularization (CNV) occurred in her right eye during the follow-up. Visual acuity decreased from 20/20 to 20/32 in left eye; from 20/20 to 20/100 in her right eye. Conclusions: we reported the natural history of acquired vitelliform lesion in PXE-related retinopathy describing the Intraretinal hyperreflective foci migration.",

keywords = "acquired vitelliform lesion, CNV, hyper-reflective foci, pigment migration, pseudoxantoma elasticum, PXE",

author = "Vittoria Murro and Mucciolo, {Dario Pasquale} and Dario Giorgio and Andrea Sodi and Federica Boraldi and Daniela Quaglino and Gianni Virgili and Stanislao Rizzo",

year = "2019",

month = sep,

day = "21",

doi = "10.1080/13816810.2019.1666882",

language = "English",

volume = "40",

pages = "385--387",

journal = "Ophthalmic genetics",

issn = "1381-6810",

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number = "4",

}

Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up. / Murro, Vittoria; Mucciolo, Dario Pasquale; Giorgio, Dario; Sodi, Andrea; Boraldi, Federica; Quaglino, Daniela; Virgili, Gianni; Rizzo, Stanislao.

In: Ophthalmic genetics, Vol. 40, No. 4, 21.09.2019, p. 385-387.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up

AU - Murro, Vittoria

AU - Mucciolo, Dario Pasquale

AU - Giorgio, Dario

AU - Sodi, Andrea

AU - Boraldi, Federica

AU - Quaglino, Daniela

AU - Virgili, Gianni

AU - Rizzo, Stanislao

PY - 2019/9/21

Y1 - 2019/9/21

N2 - Purposes: To describe the long-term follow-up of a patient affected by Pseudoxanthoma Elasticum (PXE) and acquired macular vitelliform lesions in both eyes. Material and methods: Case report Results: We reported the 9-year follow-up of a patient affected by PXE. We described the onset and the resolution of the vitelliform macular lesions which lasted 5 years. The vitelliform lesion appeared almost simultaneously in both eyes with an initial increase in size, even though asymmetrical. We detected the intraretinal migration of hyper-reflective foci in both eyes during the follow-up. Choroidal neovascularization (CNV) occurred in her right eye during the follow-up. Visual acuity decreased from 20/20 to 20/32 in left eye; from 20/20 to 20/100 in her right eye. Conclusions: we reported the natural history of acquired vitelliform lesion in PXE-related retinopathy describing the Intraretinal hyperreflective foci migration.

AB - Purposes: To describe the long-term follow-up of a patient affected by Pseudoxanthoma Elasticum (PXE) and acquired macular vitelliform lesions in both eyes. Material and methods: Case report Results: We reported the 9-year follow-up of a patient affected by PXE. We described the onset and the resolution of the vitelliform macular lesions which lasted 5 years. The vitelliform lesion appeared almost simultaneously in both eyes with an initial increase in size, even though asymmetrical. We detected the intraretinal migration of hyper-reflective foci in both eyes during the follow-up. Choroidal neovascularization (CNV) occurred in her right eye during the follow-up. Visual acuity decreased from 20/20 to 20/32 in left eye; from 20/20 to 20/100 in her right eye. Conclusions: we reported the natural history of acquired vitelliform lesion in PXE-related retinopathy describing the Intraretinal hyperreflective foci migration.

KW - acquired vitelliform lesion

KW - CNV

KW - hyper-reflective foci

KW - pigment migration

KW - pseudoxantoma elasticum

KW - PXE

U2 - 10.1080/13816810.2019.1666882

DO - 10.1080/13816810.2019.1666882

M3 - Article

C2 - 31542970

AN - SCOPUS:85072848716

VL - 40

SP - 385

EP - 387

JO - Ophthalmic genetics

JF - Ophthalmic genetics

SN - 1381-6810

IS - 4

ER -

Intraretinal hyperreflective foci in PXE-related retinopathy with acquired vitelliform lesions: a long-term follow-up

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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