Projects per year
Abstract
This research uses an urban soil geochemistry database of elemental concentration to examine the potential relationship between Standardised Incidence Rates (SIRs) of Chronic Kidney Disease (CKD) of uncertain aetiology (CKDu), and cumulative low level geogenic and diffuse anthropogenic contamination of soils with PTEs. A compositional data analysis approach was applied to determine the elemental balance(s) of the geochemical data showing the greatest association with CKDu. The research concludes that both anthropogenic and geogenic factors may be contributing influences to explain high incidences of CKDu, up to 12 times greater in some Super Output Areas (SOA) than would be expected for the average population. The role of As, Cr, Cu, Pb, Sb and Mo was highlighted, which may be linked to anthropogenic sources such as historical industrial sources, atmospheric pollution deposition and brake emissions. Geogenic factors were shown to be important in areas with elevated relative concentrations of naturally occurring potentially toxic elements (PTE).
Original language | English |
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Article number | 1000247 |
Number of pages | 7 |
Journal | Applied Computing and Geosciences |
Volume | 6 |
Early online date | 31 Mar 2020 |
DOIs | |
Publication status | Published - 01 Jun 2020 |
Event | The 8th International Workshop on Compositional Data Analysis: CoDa Work 2019 - U. Politécnica de Cataluña , Terrassa, Barcelona, Spain Duration: 03 Jun 2019 → 08 Jun 2019 Conference number: 8 https://webs.camins.upc.edu/codawork2019/ |
Keywords
- Geochemistry
- chronic kidney disease
- uncertain aetiology
ASJC Scopus subject areas
- Environmental Chemistry
- Environmental Science (miscellaneous)
- Health, Toxicology and Mutagenesis
- Pollution
- Applied Mathematics
- Modelling and Simulation
Fingerprint
Dive into the research topics of 'Investigating the influence of environmental factors on the incidence of renal disease with compositional data analysis using balances'. Together they form a unique fingerprint.Projects
- 1 Finished
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R3977GGY: Trace Element Abundance and Human Epidemiology - The Tellus Case Study<GEOG/PLANNING>
McKinley, J. (PI) & Ofterdinger, U. (CoI)
01/08/2007 → 30/06/2008
Project: Research
Activities
- 1 Invited or keynote talk at national or international conference
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Understanding the relationship between Chronic kidney disease, environmental toxins and atmospheric pollutants
McKinley, J. (Invited speaker), Mueller, U. (Contributor) & Fogarty, D. (Contributor)
30 Nov 2022Activity: Talk or presentation types › Invited or keynote talk at national or international conference
File
Profiles
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Chronic kidney disease of uncertain aetiology and its relation with waterborne environmental toxins: An investigation via compositional balances
McKinley, J., Mueller, U., Atkinson, P., Ofterdinger, U., Cox, S., Doherty, R., Fogarty, D. & Egozcue, J. J., 17 Jun 2021, Advances in Computational Algorithms and Data Analysis: Festschrift in Honour of Vera Pawlowsky-Glann. Filzmoser, P., Hron, K., Martín-Fernández, J. A. & Palarea-Albaladejo, J. (eds.). 1 ed. Switzerland: Springer, p. 285-302 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Exploring the effects of environmental toxins from air pollution on chronic kidney disease
McKinley, J., Mueller, U., Atkinson, P., Ofterdinger, U., Cox, S., Doherty, R., Fogarty, D., Egozcue, J. J. & Pawlowsky-Glahn, V., 18 Jun 2021, p. 63-70. 8 p.Research output: Contribution to conference › Abstract › peer-review
Open AccessFile -
The relationship between historical development and potentially toxic element concentrations in urban soils
McIlwaine, R., Doherty, R., Cox, S. F. & Cave, M., Jan 2017, In: Environmental Pollution . 220, p. 1036-1049 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)835 Downloads (Pure)