Investigation of the causes for the occurrence of residues of the anticoccidial feed additive nicarbazin in commercial poultry

M. O'Keeffe, E. Capurro, M. Danaher, Katrina Campbell, Christopher Elliott

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Investigations were undertaken to identify causes for the occurrence of high levels of the zootechnical feed additive nicarbazin in broiler liver at slaughter. The first investigation on 32 commercial broiler flocks involved sampling and analysis for nicarbazin ( as dinitrocarbanilide, DNC) in liver from birds during a 3-10-day period after withdrawal of nicarbazin from their feed and before commercial slaughter. DNC residues in liver samples of broilers scheduled as being withdrawn from nicarbazin for >= 6 days ranged from 20 to > 1600 mu g kg(-1) ( the specified withdrawal period for nicarbazin is 5 days and the Joint Expert Committee on Food Additives (JECFA)maximum residue limit (MRL) is 200 mu g kg(-1) liver). Further on-farm investigations on 12 of these flocks, selected on the basis of the feeding system in use and the levels of DNC residues determined in liver, identified issues in feed management contributing to elevated residues in broiler liver. A significant correlation (0.81, p
Original languageEnglish
Pages (from-to)923-934
Number of pages12
JournalFood Additives and Contaminants
Volume24
Issue number9
DOIs
Publication statusPublished - Sep 2007

ASJC Scopus subject areas

  • Food Science
  • Chemistry (miscellaneous)
  • Toxicology
  • Health, Toxicology and Mutagenesis

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