Is there an association between inter-fraction motion during prostate SABR and quality of life?

Orla Houlihan; Niamh  Clarke; Christina Agnew; Owen McLaughlin; Ciara Lyons; Aidan Cole; Joe O'Sullivan; Kevin M.  Prise; Alan R. Hounsell; Darren M Mitchell; Conor McGarry; Suneil Jain

doi:10.1016/S0167-8140(24)02965-7

Is there an association between inter-fraction motion during prostate SABR and quality of life?

Orla Houlihan, Niamh Clarke, Christina Agnew, Owen McLaughlin, Ciara Lyons, Aidan Cole, Joe O'Sullivan, Kevin M. Prise, Alan R. Hounsell, Darren M Mitchell, Conor McGarry, Suneil Jain

Research output: Contribution to journal › Meeting abstract › peer-review

Abstract

Patient-reported outcomes are important as they give a direct indication of the impact of a disease and its treatment on patients’ quality of life (QOL)[1]. With advances in radiotherapy and improved tumour outcomes in recent years, minimising treatment-related toxicities after treatment is increasingly important [2, 3]. During prostate SABR, the potential exists for movement of the rectum and bladder, as these are mobile organs at risk (OARs). This study explored whether pre-fraction CBCTs provided a better indication of patient-reported QOL scores, as measured by the Expanded Prostate Cancer Index Composite (EPIC), than the planning CT for patients in a randomised trial of SABR±elective nodal irradiation in high-risk prostate cancer (SPORT trial).

Original language	English
Article number	2830
Pages (from-to)	S2572
Number of pages	2
Journal	Radiotherapy and Oncology
Volume	194
DOIs	https://doi.org/10.1016/S0167-8140(24)02965-7
Publication status	Published - 01 May 2024

Keywords

SABR
RADIOTHERAPY
Patient Reported Outcome Measures

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

@article{b1b0ccb7ad6a47b7b1acd6b54b96447b,

title = "Is there an association between inter-fraction motion during prostate SABR and quality of life?",

abstract = "Patient-reported outcomes are important as they give a direct indication of the impact of a disease and its treatment on patients{\textquoteright} quality of life (QOL)[1]. With advances in radiotherapy and improved tumour outcomes in recent years, minimising treatment-related toxicities after treatment is increasingly important [2, 3]. During prostate SABR, the potential exists for movement of the rectum and bladder, as these are mobile organs at risk (OARs). This study explored whether pre-fraction CBCTs provided a better indication of patient-reported QOL scores, as measured by the Expanded Prostate Cancer Index Composite (EPIC), than the planning CT for patients in a randomised trial of SABR±elective nodal irradiation in high-risk prostate cancer (SPORT trial).",

keywords = "SABR, RADIOTHERAPY, Patient Reported Outcome Measures",

author = "Orla Houlihan and Niamh Clarke and Christina Agnew and Owen McLaughlin and Ciara Lyons and Aidan Cole and Joe O'Sullivan and Prise, {Kevin M.} and Hounsell, {Alan R.} and Mitchell, {Darren M} and Conor McGarry and Suneil Jain",

year = "2024",

month = may,

day = "1",

doi = "10.1016/S0167-8140(24)02965-7",

language = "English",

volume = "194",

pages = "S2572",

journal = "Radiotherapy and Oncology",