Lack of effect of glutamine administration to boost the innate immune system response in trauma patients in the intensive care unit

Jon Pérez-Bárcena, Catalina Crespí, Verónica Regueiro, Pedro Marsé, Joan M Raurich, Jordi Ibáñez, Abelardo García de Lorenzo-Mateos, José A Bengoechea

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The use of glutamine as a dietary supplement is associated with a reduced risk of infection. We hypothesized that the underlying mechanism could be an increase in the expression and/or functionality of Toll-like receptors (TLR), key receptors sensing infections. The objective of this study was to evaluate whether glutamine supplementation alters the expression and functionality of TLR2 and TLR4 in circulating monocytes of trauma patients admitted to the intensive care unit (ICU).
Original languageEnglish
Pages (from-to)R233
JournalCritical Care
Volume14
Issue number6
DOIs
Publication statusPublished - 2010

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