Lighting-up Protein-Ligand Interactions with Fluorescent PET (Photoinduced Electron Transfer) Sensor Designs

Bernard McLaughlin, A. Prasanna de Silva, Glenn D. Wright, Brian Daly, Esther M. Surender

Research output: Contribution to journalArticle

6 Citations (Scopus)
125 Downloads (Pure)

Abstract

The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), are switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations. 
Original languageEnglish
Number of pages5
JournalChemical Communications
Early online date27 Nov 2017
DOIs
Publication statusEarly online date - 27 Nov 2017

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Avidin
Bovine Serum Albumin
Lighting
Fluorescence
Ligands
Derivatives
Proteins
Electrons
Sensors

Cite this

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title = "Lighting-up Protein-Ligand Interactions with Fluorescent PET (Photoinduced Electron Transfer) Sensor Designs",
abstract = "The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), are switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations. ",
author = "Bernard McLaughlin and {de Silva}, {A. Prasanna} and Wright, {Glenn D.} and Brian Daly and Surender, {Esther M.}",
year = "2017",
month = "11",
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doi = "10.1039/C7CC05929A",
language = "English",
journal = "Chemical Communications",
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publisher = "Royal Society of Chemistry",

}

Lighting-up Protein-Ligand Interactions with Fluorescent PET (Photoinduced Electron Transfer) Sensor Designs. / McLaughlin, Bernard; de Silva, A. Prasanna; Wright, Glenn D.; Daly, Brian; Surender, Esther M.

In: Chemical Communications, 27.11.2017.

Research output: Contribution to journalArticle

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AU - de Silva, A. Prasanna

AU - Wright, Glenn D.

AU - Daly, Brian

AU - Surender, Esther M.

PY - 2017/11/27

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N2 - The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), are switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations. 

AB - The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), are switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations. 

U2 - 10.1039/C7CC05929A

DO - 10.1039/C7CC05929A

M3 - Article

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JF - Chemical Communications

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