Lighting-up Protein-Ligand Interactions with Fluorescent PET (Photoinduced Electron Transfer) Sensor Designs

Bernard McLaughlin, A. Prasanna de Silva, Glenn D. Wright, Brian Daly, Esther M. Surender

Research output: Contribution to journalArticle

11 Citations (Scopus)
186 Downloads (Pure)

Abstract

The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), are switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations. 
Original languageEnglish
Number of pages5
JournalChemical Communications
Early online date27 Nov 2017
DOIs
Publication statusEarly online date - 27 Nov 2017

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