Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)

M.J. Caslake; C.J. Packard; M. Robertson; J. Cooney; J.J. Nelson; I. Ford; Allan Gaw; J.W. Jukema; P.W. Macfarlane; D.J. Stott; J. Shepherd

doi:10.1016/j.atherosclerosis.2009.10.041

Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)

M.J. Caslake, C.J. Packard, M. Robertson, J. Cooney, J.J. Nelson, I. Ford, Allan Gaw, J.W. Jukema, P.W. Macfarlane, D.J. Stott, J. Shepherd

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Objective: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an inflammatory biomarker that circulates mainly bound to LDL. We evaluated the association of Lp-PLA(2) with vascular events in the elderly where the importance of LDL is diminished as a risk factor for coronary disease.

Original language	English
Pages (from-to)	28-34
Number of pages	7
Journal	Atherosclerosis
Volume	210
Issue number	1
DOIs	https://doi.org/10.1016/j.atherosclerosis.2009.10.041
Publication status	Published - May 2010

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.atherosclerosis.2009.10.041

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Caslake, M. J., Packard, C. J., Robertson, M., Cooney, J., Nelson, J. J., Ford, I., Gaw, A., Jukema, J. W., Macfarlane, P. W., Stott, D. J., & Shepherd, J. (2010). Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Atherosclerosis, 210(1), 28-34. https://doi.org/10.1016/j.atherosclerosis.2009.10.041

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abstract = "Objective: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an inflammatory biomarker that circulates mainly bound to LDL. We evaluated the association of Lp-PLA(2) with vascular events in the elderly where the importance of LDL is diminished as a risk factor for coronary disease.",

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Caslake, MJ, Packard, CJ, Robertson, M, Cooney, J, Nelson, JJ, Ford, I, Gaw, A, Jukema, JW, Macfarlane, PW, Stott, DJ & Shepherd, J 2010, 'Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)', Atherosclerosis, vol. 210, no. 1, pp. 28-34. https://doi.org/10.1016/j.atherosclerosis.2009.10.041

TY - JOUR

T1 - Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)

AU - Caslake, M.J.

AU - Packard, C.J.

AU - Robertson, M.

AU - Cooney, J.

AU - Nelson, J.J.

AU - Ford, I.

AU - Gaw, Allan

AU - Jukema, J.W.

AU - Macfarlane, P.W.

AU - Stott, D.J.

AU - Shepherd, J.

PY - 2010/5

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N2 - Objective: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an inflammatory biomarker that circulates mainly bound to LDL. We evaluated the association of Lp-PLA(2) with vascular events in the elderly where the importance of LDL is diminished as a risk factor for coronary disease.

AB - Objective: Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an inflammatory biomarker that circulates mainly bound to LDL. We evaluated the association of Lp-PLA(2) with vascular events in the elderly where the importance of LDL is diminished as a risk factor for coronary disease.

U2 - 10.1016/j.atherosclerosis.2009.10.041

DO - 10.1016/j.atherosclerosis.2009.10.041

M3 - Article

VL - 210

SP - 28

EP - 34

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

IS - 1

ER -

Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)

Abstract

ASJC Scopus subject areas

UN SDGs

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