Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Neus Lozano, Wafa' T Al-Jamal, Adrian Taruttis, Nicolas Beziere, Neal C Burton, Jeroen van den Bossche, Mariarosa Mazza, Eva Herzog, Vasilis Ntziachristos, Kostas Kostarelos

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)

Abstract

The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

Original languageEnglish
Pages (from-to)13256-8
Number of pages3
JournalJournal of the American Chemical Society
Volume134
Issue number32
DOIs
Publication statusPublished - 15 Aug 2012

Keywords

  • Animals
  • Gold
  • Humans
  • Liposomes
  • Metal Nanoparticles
  • Optical Imaging
  • Journal Article
  • Research Support, Non-U.S. Gov't

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