Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Neus Lozano; Wafa' T Al-Jamal; Adrian Taruttis; Nicolas Beziere; Neal C Burton; Jeroen van den Bossche; Mariarosa Mazza; Eva Herzog; Vasilis Ntziachristos; Kostas Kostarelos

doi:10.1021/ja304499q

Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Neus Lozano
, Wafa' T Al-Jamal
, Adrian Taruttis
, Nicolas Beziere
, Neal C Burton
, Jeroen van den Bossche
, Mariarosa Mazza
, Eva Herzog
, Vasilis Ntziachristos
, Kostas Kostarelos

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

Original language	English
Pages (from-to)	13256-8
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	134
Issue number	32
DOIs	https://doi.org/10.1021/ja304499q
Publication status	Published - 15 Aug 2012

Keywords

Animals
Gold
Humans
Liposomes
Metal Nanoparticles
Optical Imaging
Journal Article
Research Support, Non-U.S. Gov't

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10.1021/ja304499q

Cite this

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title = "Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues",

abstract = "The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.",

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author = "Neus Lozano and Al-Jamal, \{Wafa' T\} and Adrian Taruttis and Nicolas Beziere and Burton, \{Neal C\} and \{van den Bossche\}, Jeroen and Mariarosa Mazza and Eva Herzog and Vasilis Ntziachristos and Kostas Kostarelos",

year = "2012",

month = aug,

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doi = "10.1021/ja304499q",

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T1 - Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

AU - Lozano, Neus

AU - Al-Jamal, Wafa' T

AU - Taruttis, Adrian

AU - Beziere, Nicolas

AU - Burton, Neal C

AU - van den Bossche, Jeroen

AU - Mazza, Mariarosa

AU - Herzog, Eva

AU - Ntziachristos, Vasilis

AU - Kostarelos, Kostas

PY - 2012/8/15

Y1 - 2012/8/15

N2 - The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

AB - The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

KW - Animals

KW - Gold

KW - Humans

KW - Liposomes

KW - Metal Nanoparticles

KW - Optical Imaging

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1021/ja304499q

DO - 10.1021/ja304499q

M3 - Article

C2 - 22852749

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VL - 134

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EP - 13258

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 32

ER -

Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Abstract

Keywords

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