Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

M. Mingueneau, R. Roncagalli, C. Grégoire, Adrien Kissenpfennig, A. Miazek, C. Archambaud, Y. Wang, P. Perrin, E. Bertosio, A. Sansoni, S. Richelme, R.M. Locksley, E. Aguado

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Medicine & Life Sciences