Luminescent Terbium Contrast Agent for Bone Microdamage Detection

B.K. McMahon; P. Mauer; Colin McCoy; T.C. Lee; T. Gunnlaugsson

doi:10.1071/CH11021

Luminescent Terbium Contrast Agent for Bone Microdamage Detection

B.K. McMahon, P. Mauer, Colin McCoy, T.C. Lee, T. Gunnlaugsson

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The synthesis and photophysical evaluation of a new lanthanide luminescence imaging agent is presented. The agent, a terbium-based cyclen complex can, through the use of an iminodiacetate moiety, bind to damaged bone surface via chelation to exposed Ca(II) sites, enabling the imaging of the damage using confocal fluorescence scanning microscopy.

Original language	English
Pages (from-to)	600-603
Number of pages	4
Journal	Australian Journal of Chemistry
Volume	64
Issue number	5
DOIs	https://doi.org/10.1071/CH11021
Publication status	Published - 2011

ASJC Scopus subject areas

General Chemistry

Access to Document

10.1071/CH11021

Cite this

@article{4a6f6aa05e5343b9ac0ec02834915ac6,

title = "Luminescent Terbium Contrast Agent for Bone Microdamage Detection",

abstract = "The synthesis and photophysical evaluation of a new lanthanide luminescence imaging agent is presented. The agent, a terbium-based cyclen complex can, through the use of an iminodiacetate moiety, bind to damaged bone surface via chelation to exposed Ca(II) sites, enabling the imaging of the damage using confocal fluorescence scanning microscopy.",

author = "B.K. McMahon and P. Mauer and Colin McCoy and T.C. Lee and T. Gunnlaugsson",

year = "2011",

doi = "10.1071/CH11021",

language = "English",

volume = "64",

pages = "600--603",

journal = "Australian Journal of Chemistry",

issn = "1445-0038",

publisher = "CSIRO Publishing ",

number = "5",

}

TY - JOUR

T1 - Luminescent Terbium Contrast Agent for Bone Microdamage Detection

AU - McMahon, B.K.

AU - Mauer, P.

AU - McCoy, Colin

AU - Lee, T.C.

AU - Gunnlaugsson, T.

PY - 2011

Y1 - 2011

N2 - The synthesis and photophysical evaluation of a new lanthanide luminescence imaging agent is presented. The agent, a terbium-based cyclen complex can, through the use of an iminodiacetate moiety, bind to damaged bone surface via chelation to exposed Ca(II) sites, enabling the imaging of the damage using confocal fluorescence scanning microscopy.

AB - The synthesis and photophysical evaluation of a new lanthanide luminescence imaging agent is presented. The agent, a terbium-based cyclen complex can, through the use of an iminodiacetate moiety, bind to damaged bone surface via chelation to exposed Ca(II) sites, enabling the imaging of the damage using confocal fluorescence scanning microscopy.

U2 - 10.1071/CH11021

DO - 10.1071/CH11021

M3 - Article

SN - 1445-0038

VL - 64

SP - 600

EP - 603

JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 5

ER -

Luminescent Terbium Contrast Agent for Bone Microdamage Detection

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this