Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals

Jane McEneny, Lauren Wade, Ian Young, L. Masson, G. Duthiec, Ann McGinty, Cyril McMaster, F. Thies

Research output: Contribution to journalArticlepeer-review

71 Citations (Scopus)

Abstract

The management of overweight subjects by interventions aimed at reducing inflammation is highly desirable. To date, observational studies have identified a link between increased dietary antioxidant intake and reduced cardiovascular morbidity. However, direct trial evidence regarding the ability of antioxidants to influence inflammation is lacking. Therefore, this study examined lycopene's ability to lower systemic and high-density lipoprotein (HDL)-associated inflammation in moderately overweight middle-aged subjects. Serum was collected before and after a 12-week intervention from 54 moderately overweight, middle-aged individuals. Subjects were randomised to one of three groups: control diet (
Original languageEnglish
Pages (from-to)163–168
Number of pages6
JournalJournal of Nutritional Biochemistry
Volume24
Issue number1
Early online date21 Jul 2012
DOIs
Publication statusPublished - Jan 2013

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Clinical Biochemistry
  • Biochemistry

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