Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals

Jane McEneny; Lauren Wade; Ian Young; L. Masson; G. Duthiec; Ann McGinty; Cyril McMaster; F. Thies

doi:10.1016/j.jnutbio.2012.03.015

Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals

Jane McEneny, Lauren Wade, Ian Young, L. Masson, G. Duthiec, Ann McGinty, Cyril McMaster, F. Thies

Research output: Contribution to journal › Article › peer-review

106 Citations (Scopus)

Abstract

The management of overweight subjects by interventions aimed at reducing inflammation is highly desirable. To date, observational studies have identified a link between increased dietary antioxidant intake and reduced cardiovascular morbidity. However, direct trial evidence regarding the ability of antioxidants to influence inflammation is lacking. Therefore, this study examined lycopene's ability to lower systemic and high-density lipoprotein (HDL)-associated inflammation in moderately overweight middle-aged subjects. Serum was collected before and after a 12-week intervention from 54 moderately overweight, middle-aged individuals. Subjects were randomised to one of three groups: control diet (

Original language	English
Pages (from-to)	163–168
Number of pages	6
Journal	Journal of Nutritional Biochemistry
Volume	24
Issue number	1
Early online date	21 Jul 2012
DOIs	https://doi.org/10.1016/j.jnutbio.2012.03.015
Publication status	Published - Jan 2013

ASJC Scopus subject areas

Nutrition and Dietetics
Endocrinology, Diabetes and Metabolism
Molecular Biology
Clinical Biochemistry
Biochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jnutbio.2012.03.015

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abstract = "The management of overweight subjects by interventions aimed at reducing inflammation is highly desirable. To date, observational studies have identified a link between increased dietary antioxidant intake and reduced cardiovascular morbidity. However, direct trial evidence regarding the ability of antioxidants to influence inflammation is lacking. Therefore, this study examined lycopene's ability to lower systemic and high-density lipoprotein (HDL)-associated inflammation in moderately overweight middle-aged subjects. Serum was collected before and after a 12-week intervention from 54 moderately overweight, middle-aged individuals. Subjects were randomised to one of three groups: control diet (",

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AU - Masson, L.

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AU - McGinty, Ann

AU - McMaster, Cyril

AU - Thies, F.

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Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals

Abstract

ASJC Scopus subject areas

UN SDGs

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