Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial

Fernando Carrera; Charmaine E Lok; Angel de Francisco; Francesco Locatelli; Johannes F E Mann; Bernard Canaud; Peter G Kerr; Iain C Macdougall; Anatole Besarab; Giuseppe Villa; Isabelle Kazes; Bruno Van Vlem; Shivinder Jolly; Ulrich Beyer; Frank C Dougherty; PATRONUS Investigators; Alexander Maxwell

doi:10.1093/ndt/gfq305

Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial

Fernando Carrera, Charmaine E Lok, Angel de Francisco, Francesco Locatelli, Johannes F E Mann, Bernard Canaud, Peter G Kerr, Iain C Macdougall, Anatole Besarab, Giuseppe Villa, Isabelle Kazes, Bruno Van Vlem, Shivinder Jolly, Ulrich Beyer, Frank C Dougherty, PATRONUS Investigators, Alexander Maxwell

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

Several studies with erythropoiesis-stimulating agents claim that maintenance therapy of renal anaemia may be possible at extended dosing intervals; however, few studies were randomized, results varied, and comparisons between agents were absent. We report results of a multi-national, randomized, prospective trial comparing haemoglobin maintenance with methoxy polyethylene glycol-epoetin beta and darbepoetin alfa administered once monthly.

Original language	English
Pages (from-to)	4009-17
Number of pages	9
Journal	Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Volume	25
Issue number	12
DOIs	https://doi.org/10.1093/ndt/gfq305
Publication status	Published - Dec 2010

Bibliographical note

PATRONUS study investigator

ASJC Scopus subject areas

Nephrology
Transplantation

Access to Document

10.1093/ndt/gfq305

Cite this

Carrera, F., Lok, C. E., de Francisco, A., Locatelli, F., Mann, J. F. E., Canaud, B., Kerr, P. G., Macdougall, I. C., Besarab, A., Villa, G., Kazes, I., Van Vlem, B., Jolly, S., Beyer, U., Dougherty, F. C., PATRONUS Investigators, & Maxwell, A. (2010). Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(12), 4009-17. https://doi.org/10.1093/ndt/gfq305

Carrera, Fernando ; Lok, Charmaine E ; de Francisco, Angel et al. / Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly : a randomized comparative trial. In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2010 ; Vol. 25, No. 12. pp. 4009-17.

@article{3e4da6034a5d4547bd3a4b5ab5ba1d84,

title = "Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial",

abstract = "Several studies with erythropoiesis-stimulating agents claim that maintenance therapy of renal anaemia may be possible at extended dosing intervals; however, few studies were randomized, results varied, and comparisons between agents were absent. We report results of a multi-national, randomized, prospective trial comparing haemoglobin maintenance with methoxy polyethylene glycol-epoetin beta and darbepoetin alfa administered once monthly.",

author = "Fernando Carrera and Lok, {Charmaine E} and {de Francisco}, Angel and Francesco Locatelli and Mann, {Johannes F E} and Bernard Canaud and Kerr, {Peter G} and Macdougall, {Iain C} and Anatole Besarab and Giuseppe Villa and Isabelle Kazes and {Van Vlem}, Bruno and Shivinder Jolly and Ulrich Beyer and Dougherty, {Frank C} and {PATRONUS Investigators} and Alexander Maxwell",

note = "PATRONUS study investigator",

year = "2010",

month = dec,

doi = "10.1093/ndt/gfq305",

language = "English",

volume = "25",

pages = "4009--17",

journal = "Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association",

issn = "1460-2385",

publisher = "Oxford University Press",

number = "12",

}

Carrera, F, Lok, CE, de Francisco, A, Locatelli, F, Mann, JFE, Canaud, B, Kerr, PG, Macdougall, IC, Besarab, A, Villa, G, Kazes, I, Van Vlem, B, Jolly, S, Beyer, U, Dougherty, FC, PATRONUS Investigators & Maxwell, A 2010, 'Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial', Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, vol. 25, no. 12, pp. 4009-17. https://doi.org/10.1093/ndt/gfq305

Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial. / Carrera, Fernando; Lok, Charmaine E; de Francisco, Angel et al.
In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 25, No. 12, 12.2010, p. 4009-17.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly

T2 - a randomized comparative trial

AU - Carrera, Fernando

AU - Lok, Charmaine E

AU - de Francisco, Angel

AU - Locatelli, Francesco

AU - Mann, Johannes F E

AU - Canaud, Bernard

AU - Kerr, Peter G

AU - Macdougall, Iain C

AU - Besarab, Anatole

AU - Villa, Giuseppe

AU - Kazes, Isabelle

AU - Van Vlem, Bruno

AU - Jolly, Shivinder

AU - Beyer, Ulrich

AU - Dougherty, Frank C

AU - PATRONUS Investigators

AU - Maxwell, Alexander

N1 - PATRONUS study investigator

PY - 2010/12

Y1 - 2010/12

N2 - Several studies with erythropoiesis-stimulating agents claim that maintenance therapy of renal anaemia may be possible at extended dosing intervals; however, few studies were randomized, results varied, and comparisons between agents were absent. We report results of a multi-national, randomized, prospective trial comparing haemoglobin maintenance with methoxy polyethylene glycol-epoetin beta and darbepoetin alfa administered once monthly.

AB - Several studies with erythropoiesis-stimulating agents claim that maintenance therapy of renal anaemia may be possible at extended dosing intervals; however, few studies were randomized, results varied, and comparisons between agents were absent. We report results of a multi-national, randomized, prospective trial comparing haemoglobin maintenance with methoxy polyethylene glycol-epoetin beta and darbepoetin alfa administered once monthly.

U2 - 10.1093/ndt/gfq305

DO - 10.1093/ndt/gfq305

M3 - Article

C2 - 20522670

SN - 1460-2385

VL - 25

SP - 4009

EP - 4017

JO - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

JF - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

IS - 12

ER -

Carrera F, Lok CE, de Francisco A, Locatelli F, Mann JFE, Canaud B et al. Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2010 Dec;25(12):4009-17. doi: 10.1093/ndt/gfq305

Maintenance treatment of renal anaemia in haemodialysis patients with methoxy polyethylene glycol-epoetin beta versus darbepoetin alfa administered monthly: a randomized comparative trial

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this