Management of choroidal naevomelanocytic lesions: feasibility and safety of a virtual clinic model

Konstantinos Balaskas, Jane Gray, Peter Blows, Azita Rajai, Deidre Flaye, Tunde Peto, Mandeep S Sagoo

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


BACKGROUND: Choroidal naevomelanocytic lesions are often identified as an incidental finding by community optometrists and referred for expert evaluation in hospital eye units or specialist ocular oncology centres. Optimal management strategy is undecided and most centres err on the side of caution. Our aim was to test a virtual model of service delivery relying on interpretation of imaging test results by non-medically trained graders.

METHODS: Patients with naevomelanocytic lesions referred to Manchester Royal Eye Hospital and Moorfields Eye Hospital were retrospectively included in this study. All patients underwent imaging tests including optical coherence tomography and ultrasound and management was subsequently decided clinically. Images were anonymised and transferred to the Moorfields Eye Hospital Reading Centre and were reviewed by a trained, masked grader who reached a management decision on the basis of a specific grading protocol. Agreement between decisions made on the basis of clinical examination and imaging ('gold standard') by an expert ophthalmologist in the clinic was compared with the decisions made by a masked ophthalmologist and a masked non-medical grader based on imaging tests alone.

RESULTS: There were 102 consecutive patients included in this study. Agreement between gold-standard clinical management and decisions made by masked, non-medical grader and masked ophthalmologist on the basis of imaging test results alone was 96.1% (κ=0.97) and 100%, respectively.

CONCLUSIONS: In this pilot study, a streamlined, dedicated, virtual service for rapid assessment (within 2 weeks of referral) of choroidal naevomelanocytic lesions was shown to be feasible and safe. Such a model of service delivery may prove cost-efficient while optimising patient experience. Further prospective studies are required for formal validation of the proposed service model.

Original languageEnglish
Pages (from-to)665-670
Number of pages6
JournalBritish Journal of Ophthalmology
Issue number5
Publication statusPublished - May 2016
Externally publishedYes


  • Adult
  • Algorithms
  • Choroid Neoplasms
  • Computer Simulation
  • Decision Making
  • Delivery of Health Care
  • Diagnostic Techniques, Ophthalmological
  • Feasibility Studies
  • Humans
  • Middle Aged
  • Nevus, Pigmented
  • Ophthalmology
  • Optical Imaging
  • Optometry
  • Pilot Projects
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Ultrasonography
  • User-Computer Interface
  • Young Adult
  • Comparative Study
  • Journal Article


Dive into the research topics of 'Management of choroidal naevomelanocytic lesions: feasibility and safety of a virtual clinic model'. Together they form a unique fingerprint.

Cite this