MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases

R. C. Coll; A. A. B. Robertson; J. J. Chae; S. C. Higgins; L. S. Dungan; R. Munoz-Planillo; B. G. Monks; D. E. Croker; C. E. Sutton; A. Stutz; G. Nunez; E. Latz; D. L. Kastner; K. H. G. Mills; S. L. Masters; K. Schroder; M. A. Cooper; L. A. J. O'Neill

doi:10.1016/j.cyto.2014.07.037

MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases

R. C. Coll, A. A. B. Robertson, J. J. Chae, S. C. Higgins, L. S. Dungan, R. Munoz-Planillo, B. G. Monks, D. E. Croker, C. E. Sutton, A. Stutz, G. Nunez, E. Latz, D. L. Kastner, K. H. G. Mills, S. L. Masters, K. Schroder, M. A. Cooper, L. A. J. O'Neill

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Meeting abstract › peer-review

Original language	Undefined/Unknown
Journal	Cytokine
DOIs	https://doi.org/10.1016/j.cyto.2014.07.037
Publication status	Published - 2014

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10.1016/j.cyto.2014.07.037

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Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Dungan, L. S., Munoz-Planillo, R., Monks, B. G., Croker, D. E., Sutton, C. E., Stutz, A., Nunez, G., Latz, E., Kastner, D. L., Mills, K. H. G., Masters, S. L., Schroder, K., Cooper, M. A., & O'Neill, L. A. J. (2014). MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases. Cytokine. https://doi.org/10.1016/j.cyto.2014.07.037

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title = "MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases",

author = "Coll, {R. C.} and Robertson, {A. A. B.} and Chae, {J. J.} and Higgins, {S. C.} and Dungan, {L. S.} and R. Munoz-Planillo and Monks, {B. G.} and Croker, {D. E.} and Sutton, {C. E.} and A. Stutz and G. Nunez and E. Latz and Kastner, {D. L.} and Mills, {K. H. G.} and Masters, {S. L.} and K. Schroder and Cooper, {M. A.} and O'Neill, {L. A. J.}",

year = "2014",

doi = "10.1016/j.cyto.2014.07.037",

language = "Undefined/Unknown",

journal = "Cytokine",

issn = "1043-4666",

publisher = "Academic Press",

}

Coll, RC, Robertson, AAB, Chae, JJ, Higgins, SC, Dungan, LS, Munoz-Planillo, R, Monks, BG, Croker, DE, Sutton, CE, Stutz, A, Nunez, G, Latz, E, Kastner, DL, Mills, KHG, Masters, SL, Schroder, K, Cooper, MA & O'Neill, LAJ 2014, 'MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases', Cytokine. https://doi.org/10.1016/j.cyto.2014.07.037

TY - JOUR

T1 - MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases

AU - Coll, R. C.

AU - Robertson, A. A. B.

AU - Chae, J. J.

AU - Higgins, S. C.

AU - Dungan, L. S.

AU - Munoz-Planillo, R.

AU - Monks, B. G.

AU - Croker, D. E.

AU - Sutton, C. E.

AU - Stutz, A.

AU - Nunez, G.

AU - Latz, E.

AU - Kastner, D. L.

AU - Mills, K. H. G.

AU - Masters, S. L.

AU - Schroder, K.

AU - Cooper, M. A.

AU - O'Neill, L. A. J.

PY - 2014

Y1 - 2014

UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343021700060&KeyUID=WOS:000343021700060

U2 - 10.1016/j.cyto.2014.07.037

DO - 10.1016/j.cyto.2014.07.037

M3 - Meeting abstract

SN - 1043-4666

JO - Cytokine

JF - Cytokine

ER -

MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases

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