Abstract
A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.
Original language | English |
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Pages (from-to) | 8332-4 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 67 |
DOIs | |
Publication status | Published - 28 Aug 2012 |
Externally published | Yes |
Keywords
- Cell Line, Tumor
- Drug Delivery Systems
- Humans
- Microbubbles/therapeutic use
- Models, Biological
- Molecular Structure
- Neoplasms/therapy
- Rose Bengal/chemistry
- Ultrasonography