Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin

Edward Weaver; Edward   O’Connor; David  Cole; Andy Hooker; Shahid Uddin; Dimitrios Lamprou

Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin

Edward Weaver, Edward O’Connor, David Cole, Andy Hooker, Shahid Uddin, Dimitrios Lamprou^*

^*Corresponding author for this work

Research output: Contribution to conference › Poster › peer-review

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Abstract

Biologics play a major role in our current healthcare systems worldwide; for
example, insulins and monoclonal antibodies; however, their use is restricted to parenteral delivery with a relatively uncontrolled release profile. Using a novel microfluidic-assisted method, the encapsulation of model biologics within phospholipids (e.g., liposomes), bovine serum albumin (BSA) and trypsin (TRP), have been successfully demonstrated in this study to portray a contemporary microfluidic method for biologic medical formulation.

Original language	English
Publication status	Accepted - 01 Sept 2021
Event	2021 UKICRS Virtual Symposium - Duration: 13 Oct 2021 → 13 Oct 2021 https://www.ukicrs.org/2021-virtual-symposium.html

Conference

Conference	2021 UKICRS Virtual Symposium
Period	13/10/2021 → 13/10/2021
Internet address	https://www.ukicrs.org/2021-virtual-symposium.html

Keywords

Microfluidics
Liposomes
Biologics

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Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin
Copyright 2021 the Author.
Accepted author manuscript, 417 KBLicence: Unspecified

Sustainable microfluidic production of lipid-based nanoformulations for the delivery of biologics and small molecules
Weaver, E. (Author), Thakur, R. (Supervisor) & Lamprou, D. (Supervisor), Jul 2024
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

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title = "Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin",

abstract = "Biologics play a major role in our current healthcare systems worldwide; for example, insulins and monoclonal antibodies; however, their use is restricted to parenteral delivery with a relatively uncontrolled release profile. Using a novel microfluidic-assisted method, the encapsulation of model biologics within phospholipids (e.g., liposomes), bovine serum albumin (BSA) and trypsin (TRP), have been successfully demonstrated in this study to portray a contemporary microfluidic method for biologic medical formulation.",

keywords = "Microfluidics, Liposomes, Biologics",

author = "Edward Weaver and Edward O{\textquoteright}Connor and David Cole and Andy Hooker and Shahid Uddin and Dimitrios Lamprou",

year = "2021",

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day = "1",

language = "English",

note = "2021 UKICRS Virtual Symposium ; Conference date: 13-10-2021 Through 13-10-2021",

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TY - CONF

T1 - Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin

AU - Weaver, Edward

AU - O’Connor, Edward

AU - Cole, David

AU - Hooker, Andy

AU - Uddin, Shahid

AU - Lamprou, Dimitrios

PY - 2021/9/1

Y1 - 2021/9/1

N2 - Biologics play a major role in our current healthcare systems worldwide; for example, insulins and monoclonal antibodies; however, their use is restricted to parenteral delivery with a relatively uncontrolled release profile. Using a novel microfluidic-assisted method, the encapsulation of model biologics within phospholipids (e.g., liposomes), bovine serum albumin (BSA) and trypsin (TRP), have been successfully demonstrated in this study to portray a contemporary microfluidic method for biologic medical formulation.

AB - Biologics play a major role in our current healthcare systems worldwide; for example, insulins and monoclonal antibodies; however, their use is restricted to parenteral delivery with a relatively uncontrolled release profile. Using a novel microfluidic-assisted method, the encapsulation of model biologics within phospholipids (e.g., liposomes), bovine serum albumin (BSA) and trypsin (TRP), have been successfully demonstrated in this study to portray a contemporary microfluidic method for biologic medical formulation.

KW - Microfluidics

KW - Liposomes

KW - Biologics

M3 - Poster

T2 - 2021 UKICRS Virtual Symposium

Y2 - 13 October 2021 through 13 October 2021

ER -

Microfluidic-Mediated self-assembly of Phospholipids for the delivery of Bovine Serum Albumin and Trypsin

Abstract

Conference

Keywords

Access to Document

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Student theses

Sustainable microfluidic production of lipid-based nanoformulations for the delivery of biologics and small molecules

Cite this