Microneedles for advanced ocular drug delivery

Katie Glover; Deepakkumar Mishra; Shilpkala Gade; Lalitkumar K. Vora; Yu Wu; Alejandro J. Paredes; Ryan F. Donnelly; Thakur Raghu Raj Singh

doi:10.1016/j.addr.2023.115082

Microneedles for advanced ocular drug delivery

Katie Glover, Deepakkumar Mishra, Shilpkala Gade, Lalitkumar K. Vora, Yu Wu, Alejandro J. Paredes, Ryan F. Donnelly, Thakur Raghu Raj Singh^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Review article › peer-review

51 Citations (Scopus)

343 Downloads (Pure)

Abstract

In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, while intraocular injections are the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated with low bioavailability (

Original language	English
Article number	115082
Number of pages	25
Journal	Advanced Drug Delivery Reviews
Volume	201
Early online date	12 Sept 2023
DOIs	https://doi.org/10.1016/j.addr.2023.115082
Publication status	Published - 01 Oct 2023

Keywords

Computational modelling
Hollow microneedle
Microneedle
Ocular
Solid microneedle

ASJC Scopus subject areas

Pharmaceutical Science

Access to Document

10.1016/j.addr.2023.115082Licence: CC BY

Microneedles for advanced ocular drug delivery
Copyright 2023 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 15.8 MBLicence: CC BY

Sustained intrascleral drug delivery using hollow microneedles to target posterior segment eye diseases
Gade, S. S. (Author), Singh, T. R. R. (Supervisor) & Vora, L. (Supervisor), Dec 2024
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

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title = "Microneedles for advanced ocular drug delivery",

abstract = "In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, while intraocular injections are the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated with low bioavailability (",

keywords = "Computational modelling, Hollow microneedle, Microneedle, Ocular, Solid microneedle",

author = "Katie Glover and Deepakkumar Mishra and Shilpkala Gade and Vora, {Lalitkumar K.} and Yu Wu and Paredes, {Alejandro J.} and Donnelly, {Ryan F.} and Singh, {Thakur Raghu Raj}",

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journal = "Advanced Drug Delivery Reviews",

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AU - Glover, Katie

AU - Mishra, Deepakkumar

AU - Gade, Shilpkala

AU - Vora, Lalitkumar K.

AU - Wu, Yu

AU - Paredes, Alejandro J.

AU - Donnelly, Ryan F.

AU - Singh, Thakur Raghu Raj

PY - 2023/10/1

Y1 - 2023/10/1

N2 - In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, while intraocular injections are the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated with low bioavailability (

AB - In the field of ocular drug delivery, topical delivery remains the most common treatment option for managing anterior segment diseases, while intraocular injections are the current gold standard treatment option for treating posterior segment diseases. Nonetheless, topical eye drops are associated with low bioavailability (

KW - Computational modelling

KW - Hollow microneedle

KW - Microneedle

KW - Ocular

KW - Solid microneedle

U2 - 10.1016/j.addr.2023.115082

DO - 10.1016/j.addr.2023.115082

M3 - Review article

C2 - 37678648

AN - SCOPUS:85170641785

SN - 0169-409X

VL - 201

JO - Advanced Drug Delivery Reviews

JF - Advanced Drug Delivery Reviews

M1 - 115082

ER -

Microneedles for advanced ocular drug delivery

Abstract

Keywords

ASJC Scopus subject areas

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Student theses

Sustained intrascleral drug delivery using hollow microneedles to target posterior segment eye diseases

Cite this