Microneedles for drug delivery and monitoring

Thakur Raghu Raj Singh, Hannah Mcmillan, Karen Mooney, Ahlam Zaid Alkilani, Ryan F. Donnelly*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Abstract

Microneedles (MN) are micron-sized needles, ranging from 25 to 2000. μm in height, made of a variety of materials and shapes. Application of MNs to the skin can create micron-sized transport pathways that allow enhanced delivery of a wide range of drug molecules. The concept of MNs was first conceived in 1976; however, it was not possible to make them until the first exploitation of microelectromechanical systems (MEMS) in 1998. Therefore, this chapter will focus on the fabrication techniques of MNs using MEMS, the design and material consideration of MNs, and the application of MNs in drug delivery and monitoring biological fluids.

Original languageEnglish
Title of host publicationMicrofluidic Devices for Biomedical Applications
PublisherElsevier Inc.
Chapter6
Pages185-230
Number of pages46
ISBN (Print)9780857096975
DOIs
Publication statusPublished - 01 Jan 2013

Keywords

  • Biological fluid monitoring
  • Drug delivery
  • Microelectromechanical systems
  • Microneedles
  • Skin
  • Transdermal drug delivery

ASJC Scopus subject areas

  • Dentistry(all)
  • Medicine(all)

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