Microneedles for drug delivery and monitoring

Thakur Raghu Raj Singh; Hannah Mcmillan; Karen Mooney; Ahlam Zaid Alkilani; Ryan F. Donnelly

doi:10.1533/9780857097040.2.185

Microneedles for drug delivery and monitoring

Thakur Raghu Raj Singh, Hannah Mcmillan, Karen Mooney, Ahlam Zaid Alkilani, Ryan F. Donnelly^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

13 Citations (Scopus)

Abstract

Microneedles (MN) are micron-sized needles, ranging from 25 to 2000. μm in height, made of a variety of materials and shapes. Application of MNs to the skin can create micron-sized transport pathways that allow enhanced delivery of a wide range of drug molecules. The concept of MNs was first conceived in 1976; however, it was not possible to make them until the first exploitation of microelectromechanical systems (MEMS) in 1998. Therefore, this chapter will focus on the fabrication techniques of MNs using MEMS, the design and material consideration of MNs, and the application of MNs in drug delivery and monitoring biological fluids.

Original language	English
Title of host publication	Microfluidic Devices for Biomedical Applications
Publisher	Elsevier Inc.
Chapter	6
Pages	185-230
Number of pages	46
ISBN (Print)	9780857096975
DOIs	https://doi.org/10.1533/9780857097040.2.185
Publication status	Published - 01 Jan 2013

Keywords

Biological fluid monitoring
Drug delivery
Microelectromechanical systems
Microneedles
Skin
Transdermal drug delivery

ASJC Scopus subject areas

Dentistry(all)
Medicine(all)

Access to Document

10.1533/9780857097040.2.185

Cite this

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title = "Microneedles for drug delivery and monitoring",

abstract = "Microneedles (MN) are micron-sized needles, ranging from 25 to 2000. μm in height, made of a variety of materials and shapes. Application of MNs to the skin can create micron-sized transport pathways that allow enhanced delivery of a wide range of drug molecules. The concept of MNs was first conceived in 1976; however, it was not possible to make them until the first exploitation of microelectromechanical systems (MEMS) in 1998. Therefore, this chapter will focus on the fabrication techniques of MNs using MEMS, the design and material consideration of MNs, and the application of MNs in drug delivery and monitoring biological fluids.",

keywords = "Biological fluid monitoring, Drug delivery, Microelectromechanical systems, Microneedles, Skin, Transdermal drug delivery",

author = "Singh, {Thakur Raghu Raj} and Hannah Mcmillan and Karen Mooney and Alkilani, {Ahlam Zaid} and Donnelly, {Ryan F.}",

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language = "English",

isbn = "9780857096975",

pages = "185--230",

booktitle = "Microfluidic Devices for Biomedical Applications",

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TY - CHAP

T1 - Microneedles for drug delivery and monitoring

AU - Singh, Thakur Raghu Raj

AU - Mcmillan, Hannah

AU - Mooney, Karen

AU - Alkilani, Ahlam Zaid

AU - Donnelly, Ryan F.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Microneedles (MN) are micron-sized needles, ranging from 25 to 2000. μm in height, made of a variety of materials and shapes. Application of MNs to the skin can create micron-sized transport pathways that allow enhanced delivery of a wide range of drug molecules. The concept of MNs was first conceived in 1976; however, it was not possible to make them until the first exploitation of microelectromechanical systems (MEMS) in 1998. Therefore, this chapter will focus on the fabrication techniques of MNs using MEMS, the design and material consideration of MNs, and the application of MNs in drug delivery and monitoring biological fluids.

AB - Microneedles (MN) are micron-sized needles, ranging from 25 to 2000. μm in height, made of a variety of materials and shapes. Application of MNs to the skin can create micron-sized transport pathways that allow enhanced delivery of a wide range of drug molecules. The concept of MNs was first conceived in 1976; however, it was not possible to make them until the first exploitation of microelectromechanical systems (MEMS) in 1998. Therefore, this chapter will focus on the fabrication techniques of MNs using MEMS, the design and material consideration of MNs, and the application of MNs in drug delivery and monitoring biological fluids.

KW - Biological fluid monitoring

KW - Drug delivery

KW - Microelectromechanical systems

KW - Microneedles

KW - Skin

KW - Transdermal drug delivery

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U2 - 10.1533/9780857097040.2.185

DO - 10.1533/9780857097040.2.185

M3 - Chapter

AN - SCOPUS:84903875893

SN - 9780857096975

SP - 185

EP - 230

BT - Microfluidic Devices for Biomedical Applications

PB - Elsevier Inc.

ER -

Microneedles for drug delivery and monitoring

Abstract

Keywords

ASJC Scopus subject areas

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Polymeric microneedle systems for enhanced transdermal drug delivery

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Microneedles for drug delivery and monitoring

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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Fingerprint

Student theses

Polymeric microneedle systems for enhanced transdermal drug delivery

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