MIDA–Vinylsilanes: Selective Cross-Couplings and Applications to the Synthesis of Functionalized Stilbenes

Mark G. McLaughlin, Catherine A. McAdam, Matthew J. Cook

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A rapid and stereodefined synthesis of MIDA−boryl vinylsilanes has been achieved through the hydrosilylation of an alkynylboronic ester. The E products which contain a silyl and boryl group can be selectively cross-coupled in a two-step bidirectional sequence to provide a rapid and high-yielding synthesis of complex styrenes.
Original languageEnglish
Pages (from-to)10-13
Number of pages4
JournalOrganic Letters
Volume17
Issue number1
Early online date16 Dec 2014
DOIs
Publication statusPublished - 2015

    Fingerprint

Cite this