Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland

Stephen P McIlroy, Kevin B Dynan, John T Lawson, Christopher C Patterson, A Peter Passmore

Research output: Contribution to journalArticlepeer-review

218 Citations (Scopus)

Abstract

Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this amino acid has been shown to be due to nutritional status and methylenetetrahydrofolate reductase (MTHFR) genotype.
Original languageEnglish
Pages (from-to)2351-6
Number of pages6
JournalStroke; a journal of cerebral circulation
Volume33
Issue number10
Publication statusPublished - 01 Oct 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • General Neuroscience

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